Polytrauma and High-energy Injury Mechanisms are Associated with Worse Patient-reported Outcomes After Distal Radius Fractures

Abstract

Background Patient-reported outcomes (PROs) are increasingly relevant when evaluating the treatment of orthopaedic injuries. Little is known about how PROs may vary in the setting of polytrauma or secondary to high-energy injury mechanisms, even for common injuries such as distal radius fractures. Questions/purposes (1) Are polytrauma and high-energy injury mechanisms associated with poorer long-term PROs (EuroQol Five Dimension Three Levels [EQ-5D-3L] and QuickDASH scores) after distal radius fractures? (2) What are the median EQ-5D-3L, EQ-VAS [EuroQol VAS], and QuickDASH scores for distal radius fractures in patients with polytrauma, high-energy monotrauma and low-energy monotrauma Methods This was a retrospective study with followup by questionnaire. Patients treated both surgically and conservatively for distal radius fractures at a single Level 1 trauma center between 2008 and 2015 were approached to complete questionnaires on health-related quality of life (HRQoL) (the EQ-5D-3L and the EQ-VAS) and wrist function (the QuickDASH). Patients were grouped according to those with polytrauma (Injury Severity Score [ISS] ≥ 16), high-energy trauma (ISS < 16), and low-energy trauma based on the ISS score and injury mechanism. Initially, 409 patients were identified, of whom 345 met the inclusion criteria for followup. Two hundred sixty-five patients responded (response rate, 77% for all patients; 75% for polytrauma patients; 76% for high-energy monotrauma; 78% for low-energy monotrauma (p = 0.799 for difference between the groups). There were no major differences in baseline characteristics between respondents and nonrespondents. The association between polytrauma and high-energy injury mechanisms and PROs was assessed using forward stepwise regression modeling after performing simple bivariate linear regression analyses to identify associations between individual factors and PROs. Median outcome scores were calculated and presented. Results Polytrauma (intraarticular: β -0.11; 95% confidence interval [CI], -0.21 to -0.02]; p = 0.015) was associated with lower HRQoL and poorer wrist function (extraarticular: β 11.9; 95% CI, 0.4–23.4; p = 0.043; intraarticular: β 8.2; 95% CI, 2.1–14.3; p = 0.009). High-energy was associated with worse QuickDASH scores as well (extraarticular: β 9.5; 95% CI, 0.8–18.3; p = 0.033; intraarticular: β 11.8; 95% CI, 5.7–17.8; p < 0.001). For polytrauma, high-energy trauma, and low-energy trauma, the respective median EQ-5D-3L outcome scores were 0.84 (range, -0.33 to 1.00), 0.85 (range, 0.17–1.00), and 1.00 (range, 0.174–1.00). The VAS scores were 79 (range, 30–100), 80 (range, 50–100), and 80 (range, 40–100), and the QuickDASH scores were 7 (range, 0– 82), 11 (range, 0–73), and 5 (range, 0–66), respectively. Conclusions High-energy injury mechanisms and worse HRQoL scores were independently associated with slightly inferior wrist function after wrist fractures. Along with relatively well-known demographic and injury characteristics (gender and articular involvement), factors related to injury context (polytrauma, high-energy trauma) may account for differences in patient-reported wrist function after distal radius fractures. This information may be used to counsel patients who suffer a wrist fracture from polytrauma or high-energy trauma and to put their outcomes in context. Future research should prospectively explore whether our findings can be used to help providers to set better expectations on expected recovery. Level of Evidence Level III, therapeutic study.

Does the magnitude of injuries affect the outcome of proximal humerus fractures treated by locked plating (PHILOS)?

“…This precious finding may have influenced our Group PT-U and may, therefore, have led to the lack of significance, although the multivariable regression analyses could not confirm a correlation between EQ-VAS and ISS, age, gender or TBI. Contrary to the results of this study, van der Vliet et al [36] investigated the impact of injury severity and injury distribution on the outcome of upper extremity fracture and found that the EQ-5D is not affected by polytrauma in extraarticular fractures. Furthermore, they showed that the quick DASH is affected by increasing trauma energy [36].…”

“…Contrary to the results of this study, van der Vliet et al [36] investigated the impact of injury severity and injury distribution on the outcome of upper extremity fracture and found that the EQ-5D is not affected by polytrauma in extraarticular fractures. Furthermore, they showed that the quick DASH is affected by increasing trauma energy [36]. Since only intraarticular PHF were analyzed in this cohort, the results might not be comparable.…”

Traumakinetik – Eine Frage der Geschwindigkeitsänderung

“…Nach einem Aufprall bilden sich im Bereich des Sicherheitsgurts Hämatome. Hämatome außerhalb des Sicherheitsgurts sind Hinweise auf ein erhöhtes Risiko erheblicher Verletzungen im Bauch-, Gefäß-und Wirbelsäulenbereich [2,3,6,7,[11][12][13][14].…”

“…Insassen, die bei einem Verkehrsunfall aus dem Fahrzeug geschleudert werden, haben beim Verlassen des Fahrzeugs die gleiche Geschwindigkeit wie das Fahrzeug. Dies führt zu einem großen Impuls des Insassen, der beim Aufprall auf den Boden oder beim Anprall auf ein Hindernis nicht übertragen werden kann, sodass es zu schweren bis schwersten Verletzungen kommt [2,3,6,7].…”

Polytrauma Is Associated with Increased Three- and Six-Month Disability after Traumatic Brain Injury: A TRACK-TBI Pilot Study

“…Pathophysiologically, patients with polytrauma are at elevated risk for respiratory and multi-organ failure, 29,30 coagulopathy, 5,31 hypotension, 31 systemic inflammation, 32 and other predictors of mortality and poor outcome, in addition to delayed return to work 6 and financial burden from hospitalization. 4 Patients with polytrauma by definition have sustained additional injuries, any of which may impair long-term function, 33 confer pain and disability, 34 and therefore confound global measures of functional recovery such as the GOSE. Additionally, although we did not analyze the incidence of non-neurosurgical operative interventions, patients with polytrauma are more likely to require additional surgeries that in turn may prolong their hospitalization, rehabilitation, and recovery.…”