Polystyrene (nano)microplastics cause size-dependent neurotoxicity, oxidative damage and other adverse effects in<i>Caenorhabditis elegans</i>

Lei, Lili; Liu, Mengting; Song, Yang; Lu, Shibo; Hu, Jiani; Cao, Chengjin; Xie, Bing; Shi, Huahong; He, Defu

doi:10.1039/c8en00412a

Cited by 267 publications

(109 citation statements)

References 56 publications

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“…In terms of soil animals, there is only little information available on effects of microplastics pollution. Few studies have examined soil invertebrates, such as nematodes [92], collembolan [78,202], oligochaeta (e.g. earthworms) [201] and isopods [89].…”

Section: Soilmentioning

confidence: 99%

“…The toxicological effects of microplastics on these invertebrates are dependent on the size and particle concentration or level of exposure [87,92,201]. [92] examined the effects of different PS micro-particle sizes (0.1, 0.5, 1.0, 2.0 and 5.0 μm) on nematode (Caenorhabditis elegans) for 3 days and found strongest toxicity of 1.0 μm, due to the fact that nematodes easily accumulate moderate-sized microplastics in soil [203]. Also, the toxicity significantly downregulated the expression of unc-17 and unc-47 genes, reflecting damages to cholinergic and GABAergic neurons in nematodes [92].…”

Section: Soilmentioning

confidence: 99%

“…[92] examined the effects of different PS micro-particle sizes (0.1, 0.5, 1.0, 2.0 and 5.0 μm) on nematode (Caenorhabditis elegans) for 3 days and found strongest toxicity of 1.0 μm, due to the fact that nematodes easily accumulate moderate-sized microplastics in soil [203]. Also, the toxicity significantly downregulated the expression of unc-17 and unc-47 genes, reflecting damages to cholinergic and GABAergic neurons in nematodes [92]. However, soil oligochaeta and lumbricidae are affected by the concentrations of microplastic particle in the soil medium.…”

Section: Soilmentioning

confidence: 99%

“…One of the primary environmental risks associated with microplastics is that they are ubiquitous and bioavailable for injection by marine organisms [26,184], soil organisms [78,89,92,201,202] and plant growing on microplastic polluted soils [39,40]. Studies have reported their presence in sea animals such as seabirds, fish, sandhoppers, sea turtle, crustacean and mussel [12,21,45,118,162], soil invertebrates such as collembolan, oligochaeta (e.g.…”

Section: Introductionmentioning

confidence: 99%

“…Studies have reported their presence in sea animals such as seabirds, fish, sandhoppers, sea turtle, crustacean and mussel [12,21,45,118,162], soil invertebrates such as collembolan, oligochaeta (e.g. earthworms) and isopods [78,89,92,201,202] and in plants such as wheat plants [95]. In addition, their presence in table salts, potable water and human excreta has also been reported [6,79,80].…”

Section: Introductionmentioning

confidence: 99%

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Microplastic–toxic chemical interaction: a review study on quantified levels, mechanism and implication

et al. 2019

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Current problem facing researchers globally is microplastics as well as toxic chemical pollution of the ecosystem. Microplastics carry toxic chemicals in the ecosystem serving as a vector for transport. In this study, a review of the literature has been conducted with the following objectives: (1) to summarize the concentrations of toxic chemicals such heavy metals and hydrophobic organic contaminants sorped on microplastics; (2) to evaluate their spatial distribution regarding adsorbed contaminant; (3) to discuss plausible mechanism by which microplastics adsorp or desorp toxic chemicals in the environment; (4) to discuss implications of their occurrence in air, water and soil media; and (5) to discuss the impact of ingested microplastics to human health. Microplastics are ubiquitous environmental contaminant. Concentrations of sorped toxic chemical varied by location which represents a local problem; industrialized areas (especially areas experiencing crude oil-related activities or have history of crude oil pollution) have higher concentrations than less industrialized areas. Ingestion of microplastics has been demonstrated in a range of marine and soil organisms as well as edible plants, thus possibly contaminating the base of the food web. Potential health effect to human is by particle localization, chemical toxicity and microbial toxins. We conclude by highlighting the gap in knowledge and suggesting key future areas of research for scientists and policymakers.

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Section: Soilmentioning

confidence: 99%

Section: Soilmentioning

confidence: 99%

Section: Soilmentioning

confidence: 99%

Section: Introductionmentioning

confidence: 99%

Section: Introductionmentioning

confidence: 99%

See 3 more Smart Citations

Microplastic–toxic chemical interaction: a review study on quantified levels, mechanism and implication

et al. 2019

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Microplastics: A Global Water Pollution Problem

Weinstein

Viado

Leads

et al. 2019

Encyclopedia of Water

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Microscopic particles of plastic, known as microplastics, have become a ubiquitous contaminant in the environment. Their presence in the marine environment has been correlated to the exponential increase in global plastic production over the past 70 years and the subsequent increased abundance of plastic litter in the oceans. Other sources of microplastics include synthetic microfibers associated with the washing of textiles and tire particles associated with the abrasion and wear of the tread on automobile tires. Microplastics are recognized as contaminants of emerging concern because they occupy the same size fraction as plankton and sediment, making them bioavailable to a wide range of organisms, and they have the potential to adversely impact environmental health. Ingestion of microplastics by humans is likely, but confounding any assessment of health impacts is the lack of estimates on the total human exposure to these particles. This article will review the magnitude of plastic production and waste, provide an overview of the major sources of microplastics in the aquatic environment and the hazards they pose to both environmental and human health, and present a case study of ongoing efforts to characterize the sources and fate of microplastic contamination in Charleston Harbor, SC, USA.

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A one‐step method to manufacture biodegradable poly (butylene adipate‐co‐terephthalate) bead foam parts

Cai

Bai

2021

Polymers for Advanced Techs

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Pollution caused by waste plastic, particularly from the foam packages, is increasingly worse, and utilizing biodegradable material is considered a promising solution to handle this environmental issue. Poly (butylene adipate‐co‐terephthalate) (PBAT) is a typical environment‐friendly polymer due to the recognized biodegradability and excellent mechanical performance. However, there have been very few works preparing PBAT bead foams via the supercritical fluid foaming technology, and the related foaming behavior is still unclear. In this study, we foamed PBAT and PBAT‐polylactide (PLA) beads using supercritical carbon dioxide (Sc‐CO2) as a foaming agent, and the foaming behaviors of beads as well as the mechanical properties of bead foam parts manufactured by one‐step foaming method were systematically investigated. The incorporation of PLA enhanced the mechanical properties of the composition. At the optimal foaming conditions, the expansion ratio and cell density of PBAT/PLA foam were 13.44 and 4.08 × 108 cells/cm3, respectively. Benefitting from the uniform cell structure, the bead foam part showed excellent resilience and elasticity with adhesive strength of 0.57 MPa and compression strength of 1.05 MPa. Meanwhile, PBAT and PBAT‐PLA foam parts had high surface quality and good interbead sintering properties. PBAT can be a promising substitute for traditional non‐polymer foams for packaging, household, and automobile fields.

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Polystyrene (nano)microplastics cause size-dependent neurotoxicity, oxidative damage and other adverse effects inCaenorhabditis elegans

Abstract: (Nano)microplastics induce neurotoxicity and oxidative damage.

Cited by 267 publications

References 56 publications

Microplastic–toxic chemical interaction: a review study on quantified levels, mechanism and implication

Microplastic–toxic chemical interaction: a review study on quantified levels, mechanism and implication

Microplastics: A Global Water Pollution Problem

A one‐step method to manufacture biodegradable poly (butylene adipate‐co‐terephthalate) bead foam parts

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