Polystyrene Microcarriers Coated with a Combination of Adhesion-Promoting Peptides

Abstract

ABSTRACT. Polystyrene culture dishes and polystyrene microcarriers were coated with two different peptides -Pronectin-F and polylysine, alone and in combination. Each of the two peptides alone supported cell attachment but cell spreading occurred only on Pronectin-F. When the two peptides were used in combination, the effect was synergistic. Attachment and spreading occurred at lower concentrations of peptides when they were used in combination than when they were used individually.