Polyserositis (pericarditis and bilateral pleural effusion) after COVID-19 mRNA vaccine

Korzeniowska, Katarzyna; Cieślewicz, Artur; Flotyńska, Anna; Jabłecka, Anna

doi:10.5603/hcp.a2022.0001

Cited by 3 publications

(2 citation statements)

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“…However, unlike our case, pleural effusion, in that case, was part of a multisystemic inflammatory syndrome. Recently, Two cases were reported describing polyserositis involving pericardial and pleural effusion [11,14]. A hemorrhagic variant of pleural effusion was also reported [4].…”

Section: Discussionmentioning

confidence: 98%

A Possible Association Between COVID-19 Vaccine and Complicated Pleural Effusion: A Case Report

Oudah,

Abu-Abaa,

Al-Ameri

et al. 2023

Cureus

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As COVID-19 vaccines gain more prevalence, previously unrecognized side effects continue to be reported. We report a case of 78 male with no significant past medical history who was found to have a unilateral pleural effusion with symptoms that started two days after the administration of a COVID-19 vaccine. The initial presumption was bacterial pneumonia with parapneumonic effusion. However, the lack of clinical response prompted surgical intervention, and a diagnosis of empyema was established. No evidence of infectious etiology was found. This case helps to support the previously limited evidence in the recent medical literature that suggests a possible association between COVID-19 vaccines and pleurisy/effusion.

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Section: Discussionmentioning

confidence: 98%

A Possible Association Between COVID-19 Vaccine and Complicated Pleural Effusion: A Case Report

Oudah,

Abu-Abaa,

Al-Ameri

et al. 2023

Cureus

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“…Myocarditis and pericarditis with or without coexisting pleural effusions are some of the rarer adverse events encountered in individuals receiving the BNT162b2 vaccination, and if encountered, are usually observed in men under 40 years old in the first week following injection of the second primary series dose or first booster dose, with most booster doses likely administered at least 5 months after completing the primary vaccination [ 4 , 5 , 6 , 14 , 15 , 16 , 17 ]. Additionally, a rare case of latent herpes zoster reactivation has been published, linked to the administration of the mRNA COVID-19 vaccine, where in rare cases the presence of VZV can be associated with pleural effusions [ 18 , 19 ].…”

Section: Discussionmentioning

confidence: 99%

Unilateral Pleural Effusion after Third Dose of BNT162b2 mRNA Vaccination: Case Report

Athanasiou

Antonoglou

Ioannou

et al. 2023

JPM

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Vaccination remains the best strategy against coronavirus disease 2019 (COVID-19) in terms of prevention. The efficacy and safety of COVID-19 vaccines is supported by well-designed clinical trials that recruited many participants. It is well-known that vaccination is associated with local side effects related to the injection site, and mild, systemic side effects. However, there has been an increase in the occurrence of what is known as infrequent adverse effects in the population of vaccinated individuals in real life. We present the case of a 46-year-old woman with no past medical history, who presented with a sharp chest pain with deep inspiration, a few days after receiving the third dose of the Pfizer-BioNTech COVID-19 mRNA vaccine (BNT162b2). There is an association between the BNT16b2 vaccination and myocarditis, pericarditis, and even bilateral pleural effusions. To the best of our knowledge, this is the first report featuring a unilateral pleural effusion in a patient with no known past medical history, who did not develop cardiac involvement nor have any viral infection. The aim of our report is to inform health professionals of the possibility of encountering this rare adverse event in their daily practice, as the population of individuals who are receiving additional vaccine doses is increasing steadily.

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Tozinameran

2023

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Polyserositis (pericarditis and bilateral pleural effusion) after COVID-19 mRNA vaccine

Cited by 3 publications

References 0 publications

A Possible Association Between COVID-19 Vaccine and Complicated Pleural Effusion: A Case Report

A Possible Association Between COVID-19 Vaccine and Complicated Pleural Effusion: A Case Report

Unilateral Pleural Effusion after Third Dose of BNT162b2 mRNA Vaccination: Case Report

Tozinameran

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