2023
DOI: 10.1002/pat.6203
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Polysaccharides based biopolymers for biomedical applications: A review

Nazish Jabeen,
Muhammad Atif

Abstract: Polysaccharides are a class of natural biopolymers that have attracted significant attention due to their unique properties, which make them attractive for use in a wide range of applications. These biopolymers have an important role in our daily life, and designing biomaterials for biomedical applications requires careful consideration of factors such as biocompatibility, biodegradability, renewability, affordability, and availability, all of which can be achieved with polysaccharides. This review paper focus… Show more

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Cited by 15 publications
(7 citation statements)
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“…Polysaccharides are a promising class of material for controlled therapeutic delivery because they are relatively inexpensive, available at scale, offer diverse chemistries and molecular weights, and demonstrate good biocompatibility and biodegradability 19,20 . A library of cellulose-based polysaccharides of varied molecular weights were screened in-vitro to identify compositions providing cargo diffusion kinetics appropriate to slow the release of virus in the brain.…”
Section: Resultsmentioning
confidence: 99%
“…Polysaccharides are a promising class of material for controlled therapeutic delivery because they are relatively inexpensive, available at scale, offer diverse chemistries and molecular weights, and demonstrate good biocompatibility and biodegradability 19,20 . A library of cellulose-based polysaccharides of varied molecular weights were screened in-vitro to identify compositions providing cargo diffusion kinetics appropriate to slow the release of virus in the brain.…”
Section: Resultsmentioning
confidence: 99%
“…Hemicelluloses, a valuable biomaterial, contain various polysaccharides, such as arabinan, arabinogalactan, arabinoxylan, galactose, glucose, glucomannan, glucuronoxylans, mannanose, xylans, and xyloglucans within plant cell walls [32]. It has been formed by monosaccharide units (pentoses, hexoses, acetylated sugars, and uronic acid).…”
Section: Valorization Of Oyster By-productsmentioning
confidence: 99%
“…It has been formed by monosaccharide units (pentoses, hexoses, acetylated sugars, and uronic acid). The structure of hemicelluloses is formed through the arrangement of cell wall matrix, which consists of β-(1,4)-linked pyranosyl units, leading to cellulose cross-linked hydrogen bonding [32]. Lignin, although the least abundant yet intricate polymer, acts as a binder, filling the gaps between cellulose and hemicelluloses [19].…”
Section: Valorization Of Oyster By-productsmentioning
confidence: 99%
“…8.1. Tissue-Targeting Design, Surface Functionalization, and Controlled Release Passive (increased accumulation owing to passive physiological variables) and active (application of ligands to a specific target) diffusion are the two methods that may be used for concentrating medications to a particular area of interest [163]. The surface modification of drug carriers with bioactive compounds that interact with cell receptors and that are adsorbed, coated, conjugated, or connected to them demonstrates a preference for a certain cell or tissue type, which may increase medicine absorption.…”
Section: Consideration Of General Mechanismsmentioning
confidence: 99%