Polysaccharide-based scaffold for tissue-regeneration

Rimondo, Stefano; Perale, Giuseppe; Rossi, Filippo

doi:10.1016/b978-0-08-102555-0.00006-6

Cited by 5 publications

(3 citation statements)

References 66 publications

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“…CS is a linear and sulfated polysaccharide consisting of repeating disaccharide units of β-(1,4)-D-glucuronic acid and β-(1,3)-N-acetylgalactosamine, which are usually covalently linked to proteins, forming proteoglycans [130][131][132]. Furthermore, depending on the position of the sulfate group on the polysaccharide backbone, CS can be classified into CS-A (carbon 4), CS-C (carbon 6), CS-E (both carbon 4 and 6), CS-D (position 6 of N-acetylgalactosamine and position 4 of D-glucuronic acid), and CS-B (position 4 of N-acetylgalactosamine and position 2 of D-glucuronic acid) [130,133].…”

Section: Marine Glycosaminoglycans For Neuroprotectionmentioning

confidence: 99%

Marine Biocompounds for Neuroprotection—A Review

2020

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While terrestrial organisms are the primary source of natural products, recent years have witnessed a considerable shift towards marine-sourced biocompounds. They have achieved a great scientific interest due to the plethora of compounds with structural and chemical properties generally not found in terrestrial products, exhibiting significant bioactivity ten times higher than terrestrial-sourced molecules. In addition to the antioxidant, anti-thrombotic, anti-coagulant, anti-inflammatory, anti-proliferative, anti-hypertensive, anti-diabetic, and cardio-protection properties, marine-sourced biocompounds have been investigated for their neuroprotective potential. Thus, this review aims to describe the recent findings regarding the neuroprotective effects of the significant marine-sourced biocompounds.

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Section: Marine Glycosaminoglycans For Neuroprotectionmentioning

confidence: 99%

Marine Biocompounds for Neuroprotection—A Review

2020

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“…They can be used instead of synthetically produced additives in cosmetics and food products and may replace commonly used emulsifiers because of their water-binding capacity or rather hydrocolloid properties [1][2][3][4][5]. Furthermore, EPSs may play a future role in applications like tissue engineering, drug delivery systems, and other medical applications [6][7][8][9][10] or even fields like biofuel research [11], as they are usually involved in the formation of biofilms [12][13][14][15][16][17][18][19].…”

Section: Introductionmentioning

confidence: 99%

Analysis of Structural and Functional Differences of Glucans Produced by the Natively Released Dextransucrase of Liquorilactobacillus hordei TMW 1.1822

Schmid

Wefers

Vogel

et al. 2020

Appl Biochem Biotechnol

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The properties of the glucopolymer dextran are versatile and linked to its molecular size, structure, branching, and secondary structure. However, suited strategies to control and exploit the variable structures of dextrans are scarce. The aim of this study was to delineate structural and functional differences of dextrans, which were produced in buffers at different conditions using the native dextransucrase released by Liquorilactobacillus (L.) hordei TMW 1.1822. Rheological measurements revealed that dextran produced at pH 4.0 (M W = 1.1 * 10 8 Da) exhibited the properties of a viscoelastic fluid up to concentrations of 10% (w/v). By contrast, dextran produced at pH 5.5 (M W = 1.86 * 10 8 Da) was gel-forming already at 7.5% (w/v). As both dextrans exhibited comparable molecular structures, the molecular weight primarily influenced their rheological properties. The addition of maltose to the production assays caused the formation of the trisaccharide panose instead of dextran. Moreover, pre-cultures of L. hordei TMW 1.1822 grown without sucrose were substantial for recovery of higher dextran yields, since the cells stored the constitutively expressed dextransucrase intracellularly, until sucrose became available. These findings can be exploited for the controlled recovery of functionally diverse dextrans and oligosaccharides by the use of one dextransucrase type.

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“…Pullulan is a natural water-soluble polysaccharide with repeating units of malt triose residues extracted from the yeast-like fungus aureobasidium [24,25]. Due to its significant role in reducing ionic surface tension, sodium dodecylbenzene sulfonate (SDBS) is widely used in household detergents [26].…”

mentioning

confidence: 99%

Preparation and Characterization of Superabsorbent Polymers (SAPs) Based on PUL-g- AM/AA by Microwave Irradiation

Dhahir,

Braihi,

Habeeb

2024

Preprint

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A microwave technique prepared a superabsorbent polymer (SAP) by grafting two hydrophilic monomers onto a polysaccharide substrate. The monomers used are acrylic acid (AA) or acrylamide (AM) to graft onto a pullulan substrate (PUL) to form PUL-g- AA (SAP1) and PUL-g- AM (SAP2), respectively. The monomers (AM/AA) graft together onto a PUL substrate to form PUL-g-(AM/AA) (SAP3). Grafting parameters such as grafting efficiency with percentage, conversion of monomer to polymer, gel content, water retention, water adsorption capacity, and swelling kinetics were determined. Additionally, the effect of environmental pH (2, 4, 7, 9, and 12) and sodium dodecylbenzene sulfonate (SDBS) surfactant was evaluated, where SDBS was added by 1,2,3,4 and 5 mM to form (SAP4 to SAP8). FTIR results show that AM grafted on PUL through an aliphatic C-N bond, while AA grafting occurred through a single C-C bond. The grafting efficiency with AM is higher than with AA, as well as their gel contents. Water absorbance capacity increased with grafting of AA or AM separately, and water retention was enhanced. The highest absorbent capacity, water retention, gel content, and grafting parameters values were obtained with 3 mM SDBS content and pH7. The swelling kinetics showed that the increases in the theoretical and experimental swelling equilibriums were 72 % and 82%, respectively, at SAP6 compared to the values of these parameters in SAP3. The water absorption capacity of the hydrogel increases with increasing pH to 7 and then gradually decreases. XRD improves the crystallinity and crystalline size of the hydrogel after grafting polymerization for AM/AA into PUL, in addition to enhancing thermal stability. On the contrary, FE-SEM demonstrated that SDBS improves the porosity and pore size of the hydrogel surface in SAP6.

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Polysaccharide-based scaffold for tissue-regeneration

Cited by 5 publications

References 66 publications

Marine Biocompounds for Neuroprotection—A Review

Marine Biocompounds for Neuroprotection—A Review

Analysis of Structural and Functional Differences of Glucans Produced by the Natively Released Dextransucrase of Liquorilactobacillus hordei TMW 1.1822

Preparation and Characterization of Superabsorbent Polymers (SAPs) Based on PUL-g- AM/AA by Microwave Irradiation

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