Polypoid type of laryngeal sarcoidosis - case report and review of the literature

Abstract

A 45-year-old mentally retarded woman was discovered to produce a stridor upon inhalation. Fiberoptic laryngoscopic study revealed a smooth-surfaced, wide, and pedunculated tumor on the right arytenoid and the right aryepiglottic fold. Histopathological study revealed that the tumor was characterized by granulomatous inflammation. The condition was diagnosed as laryngeal sarcoidosis. The tumor was resected surgically. Surgical resection of the tumor and injection of corticosteroid should be performed for polypoid-type laryngeal sarcoidosis. The case is discussed in detail, along with a review of the literature pertaining to sarcoidosis of the larynx.

Sarcoidosis and its otolaryngological implications

“…The diVerential diagnosis of laryngeal sarcoidosis includes epiglottitis, granulomatous laryngitis of another cause, including tuberculosis, histoplasmosis, blastomycosis, coccidioidomycosis, syphilis and actinomycosis, malignant neoplasm, cartilaginous tumours and rare diseases of the larynx such as Wegener's granulomatosis and amyloidosis [27][28][29][30][31][32][33][34][35][36][37].…”

“…Treatment depends on the degree of the symptoms and there are the following possible options [6,8,[27][28][29][30][31][32][33][34][35][36][37]:…”

Endoscopic Airway Management of Laryngeal Sarcoidosis

“…10,19 Combining intralesional corticosteroid injections with laser ablation and/or photoreduction is a natural progression of these techniques, but this combination has been described only in case reports and small series. 3,20 Treatment efficacies are therefore unknown, and management of laryngeal sarcoidosis with minimally invasive laryngoscopic surgery remains controversial. We report the largest single-institution series, to our knowledge, of laryngeal sarcoidosis cases treated early with intralesional steroid therapy combined with minimally invasive endoscopic laser surgery.…”

Unusual Supraglottic Lesion

“…[16,17,18,19,20] As mentioned in this case report, microlaryngeal surgery can provide a better outcome for the patient.…”