Polyphenols: Chemistry, bioavailability, bioactivity, nutritional aspects and human health benefits: A review

El-Saadony, Mohamed T.; Yang, Tao; Saad, Ahmed M.; Alkafaas, Samar Sami; Elkafas, Sara Samy; Eldeeb, Gehad S.; Mohammed, Dina Mostafa; Salem, Heba M.; Korma, Sameh A.; Loutfy, Samah A.; Alshahran, Mohammad Y.; Ahmed, Ahmed Ezzat; Mosa, Walid F.A.; Abd El-Mageed, Taia A.; Ahmed, Atef F.; Fahmy, Mohamed A.; El-Tarabily, Marawan K.; Mahmoud, Reda M.; AbuQamar, Synan F.; El-Tarabily, Khaled A.; Lorenzo, José M.

doi:10.1016/j.ijbiomac.2024.134223

International Journal of Biological Macromolecules

2024

DOI: 10.1016/j.ijbiomac.2024.134223

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Polyphenols: Chemistry, bioavailability, bioactivity, nutritional aspects and human health benefits: A review

Mohamed T. El-Saadony,

Tao Yang,

Ahmed M. Saad

et al.

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Cited by 3 publications

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Protein/polysaccharide based oral delivery system for precise targeting of polyphenols and carotenoids

Jiang,

Zhai,

Zhu

et al. 2024

Food Bioscience

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Protein/polysaccharide based oral delivery system for precise targeting of polyphenols and carotenoids

Jiang,

Zhai,

Zhu

et al. 2024

Food Bioscience

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Facile One-Pot Conversion of (poly)phenols to Diverse (hetero)aryl Compounds by Suzuki Coupling Reaction: A Modified Approach for the Synthesis of Coumarin- and Equol-Based Compounds as Potential Antioxidants

Joy,

Kovalev,

Shabunina

et al. 2024

Antioxidants

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A series of 16 (hetero)aryl compounds based on coumarin and equol has been efficiently synthesized by exploring the palladium-catalyzed Suzuki cross-coupling reactions. Polyphenol based on coumarin (4-methyl-7-hydroxy coumarin) was initially converted to corresponding coumarin imidazylate and then subjected to Suzuki coupling reaction with 4-methoxyphenylboronic acid to obtain the coupled product. This modified approach was later developed into a one-pot methodology by directly reacting the polyphenol with 1,1-sulfonyldiimidazole (SDI) and boronic acid in situ to obtain the Suzuki coupled product in one step. Moreover, an array of (poly)phenols based on coumarin and equol were later converted to diverse (hetero)aryl compounds by this optimized step-economic protocol. The synthesized compounds were then subjected to the screening of their potential antioxidant activities by 2,2-diphenyl-1-picrylhydrazyl (DPPH) assay. In our investigation, the compounds 4ah, 4eh, 4gh and 4hh exhibited promising antioxidant potential when compared to the reference standard, butylated hydroxytoluene (BHT). Structure activity relationship (SAR) studies revealed the importance of the presence of electron-donating substituents in enhancing the antioxidant activity of the synthesized compounds.

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Aqua Extracts of Lyophilized Sea Buckthorn Modify Fermentation and Quality Properties of Set-Type Yogurt

Silyvridou,

Bari,

Georgopoulou

et al. 2024

Applied Sciences

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Sea buckthorn is a promising ingredient for the food industry because it is a good source of vitamins, polyphenols, phytosterols, etc. In this research, it is the first time that aqueous extracts of lyophilized sea buckthorn (LSB) 0%, 0.5%, 1%, 2%, and 3% w/w were used to enrich set-type yogurts. Therefore, fermentation kinetics, hardness, color, titratable acidity, syneresis, water holding capacity, total phenolic content microstructure, and sensory analysis were investigated. Extracts of lyophilized sea buckthorn shorten the yogurt fermentation time, change the microstructure, reduce syneresis, and increase water-holding capacity compared to plain yogurt. Also, the titratable acidity for all yogurts remained the same but the total phenolic content of yogurts increased as the concentration of extracts from lyophilized sea buckthorn increased. The color parameters of the fortified set-type yogurts were affected by the color of the sea buckthorn extract with increasing a* and b* values according to extract concentrations. Finally, yogurts fortified with 0.5% and 1.0% w/w extracts of LSB have good quality characteristics, increased total phenolic content, and higher scores of being liked compared to the rest of the enriched samples. This study could increase the knowledge of the uses of aqueous extracts of lyophilized sea buckthorn in dairy products.

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Polyphenols: Chemistry, bioavailability, bioactivity, nutritional aspects and human health benefits: A review

Cited by 3 publications

References 235 publications

Protein/polysaccharide based oral delivery system for precise targeting of polyphenols and carotenoids

Protein/polysaccharide based oral delivery system for precise targeting of polyphenols and carotenoids

Facile One-Pot Conversion of (poly)phenols to Diverse (hetero)aryl Compounds by Suzuki Coupling Reaction: A Modified Approach for the Synthesis of Coumarin- and Equol-Based Compounds as Potential Antioxidants

Aqua Extracts of Lyophilized Sea Buckthorn Modify Fermentation and Quality Properties of Set-Type Yogurt

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