Polyphenolic profile by FIA/ESI/IT/MSⁿ and antioxidant capacity of the ethanolic extract from the barks of Maytenus cajalbanica (Borhidi & O. Muñiz) Borhidi & O. Muñiz

Abstract

Medium and high polarity extracts from Maytenus species are known to contain polyphenolic compounds such as proanthocyanidins. The high polarity and structural complexity of these compounds make very difficult their isolation even by modern chromatographic techniques. Maytenus cajalbanicaSo far, there are reports neither of phytochemical work nor of biological evaluation of extracts from this subspecies. The goal of this work is to determine the polyphenolic profile and the antioxidant capacity of the ethanolic extract from the barks of Maytenus cajalbanica.FIA/ESI/IT/MS n analysis allowed the identification of 5 flavan-3-ol monomers, 33 proanthocyanidins, 2 free flavonoids and their respective glycosides as major compounds of the ethanolic extract, which showed a strong radical scavenging capacity and a significant ferric reduction power. FIA/ESI/IT/MS n technique led the rapid, effective and sensitive determination of the polyphenolic profile of Maytenus cajalbanica without previous separation.

HPLC-MS/MS targeting analysis of phenolics metabolism and antioxidant activity of extractions from Lycium barbarum and its meal using different methods

“…Flavonoid molecular ions can be lost by neutral fragmentation (H 2 O, CO, CO 2 ). For example, in apigenin 7-O-hexose with a relative molecular mass of 432, H was prone to lost in the negative scan mode; and m/z 431.0982 [M-H]and m/z 311.0583 [M-H-3CO-2H 2 O]were detected (Pino et al, 2020). Notably, pinocembrin was reported for the first time from L. barbarum.…”

Antioxidant and Antiproliferative Potentials of Ficus glumosa and Its Bioactive Polyphenol Metabolites

“…In the present study, epicatechin (4), procyanidin B2 dimer (5), catechin (6), (epi)afzelechin-(4-8)-(epi)catechin (7), cinchonain II (8), and cinchonain I (10) were tentatively identified in this species and they were previously reported with some biological importance. They possess antioxidant, anti-inflammatory, and antiproliferative properties for the case of catechin (6) and epicatechin (4) [63], procyanidin B2 dimer (5) [64], and (epi)afzelechin-(4-8)-(epi)catechin ( 7) [65]. Further, cinchonain I (10) and II (8) compounds are reported to depict good antioxidant potential [66,67].…”

Isolation and Identification of Phytocompounds from Maytenus dhofarensis and Their Biological Potentials

“…Several members of this genus are used in traditional medicine to treat cancer [ 2 ], gastric ulcers [ 3 ], and arthritis [ 4 ]. Maytenus species are known to contain a diverse group of triterpenoids [ 5 , 6 , 7 ], flavonoids [ 8 , 9 ], tannins [ 10 ], lignans [ 11 , 12 ], dihydro-β-agarofurans [ 4 , 13 , 14 ] and sesquiterpene pyridine alkaloids [ 15 , 16 , 17 ] that display remarkable structural diversities and cytotoxicity [ 18 , 19 , 20 , 21 , 22 ], as well as insecticidal [ 23 ], antitumor-promoting [ 13 ], MDR-reverting [ 24 , 25 , 26 ], antitubercular [ 27 ], neuroprotective [ 28 ], immunosuppressive [ 29 ], anti-HIV [ 30 ], anti-inflammatory [ 18 ], and medicinal properties [ 3 , 31 , 32 , 33 , 34 , 35 , 36 , 37 ].…”