Polyphenol-rich blackcurrant extract prevents inflammation in diet-induced obese mice

Metabolic Effects of Berries with Structurally Diverse Anthocyanins

“…Previously, hypoglycemic effects of maqui berry were reported for supraphysiological levels of supplementation with the anthocyanin-enriched extract (100–500 mg/kg) and purified delphinidin 3-sambubioside-5-glucoside (425 mg/kg) [45]. Beneficial metabolic effects of black currant anthocyanins have been also described [15,46]. We observed a similar outcome from consumption of blueberry monoglycosylated delphinidins, malvidins, and petunidins (non-acylated) as compared to the Concord grape (acylated).…”

Influence of maternal obesity, diet and exercise on epigenetic regulation of adipocytes

“…These phenotypes were associated with reduced leptin (adipocyte derived enhancer of energy expenditure) and peroxisome proliferator-activated receptor gamma co-activator 1 alpha (Ppargc1α) mRNA levels, and differential methylation patterns of Leptin and Ppargc1α promoters in adipocytes from apple-supplemented rats. Other bioactive phenolics, such as anthocyanins found in dark color fruits, modulate epigenetic pathways to reduce HF diet-induced inflammation (Benn et al, 2014) and cancer risk (Fimognari et al, 2008; Gerhauser, 2008; Wang et al, 2013a). However no studies have shown epigenetic modulations of anthocyanin on adipocyte differentiation and metabolism leading to obesity.…”

Prunus mahaleb L. fruit extracts: a novel source for natural food pigments

“…Blackcurrant is a berry fruit well known as a rich source of anthocyanin and phenolic compounds and popular as a colorant, flavoring and preserver in food and beverages for human consumption. Moreover, recent studies suggested blackcurrant exerts antioxidant and anti-inflammatory activity and has potential health benefits against hypertension, cardiovascular disease, neurodegenerative disease and ocular disease [65,66]. Mfce's free-radical scavenging activity against ABTS ·+ radical (Table 5), when expressed as mg TE/mL of extract, resulted 111.782 ± 7.5 mg of TE per mL, in the same range as those reported by Bermúdez-Soto et al [42] for chokeberry, elderberry and blackcurrant fruit juice concentrates.…”