Polyphenol-enriched oolong tea increases fecal lipid excretion

Abstract

Objective: To assess possibility of polyphenol-enriched oolong tea to reduce dietary lipid absorption in humans. Design: Twelve healthy adult subjects, three males and nine females, aged (mean7s.d.) 22.071.8 years, respectively, were randomly divided into two groups. The participants were followed a double-blind placebo-controlled crossover design, including 7-day washout periods and 10-day treatment periods. During the treatment periods, subjects were given about 38 g of lipids from potato chips (19 g each within 30 min after lunch and dinner) and total 750 ml beverages (placebo-or polyphenolenriched oolong tea) at three meals. Blood samples were collected for biochemical examination at days 8, 18, 25 and 35 of the study period. On the last 3 days of each treatment period, feces were collected to measure the excretion of lipids. Results: Lipid excretion into feces was significantly higher in the polyphenol-enriched oolong tea period (19.3712.9 g/3day) than in the placebo period (9.477.3 g/3day) (Po0.01). Cholesterol excretion tended to increase in polyphenol-enriched oolong tea period (1.871.2 g/3day) compared with that of placebo (1.270.6 g/3day) (P ¼ 0.056). Conclusions:The results of this study indicated that polyphenol-enriched oolong tea could increase lipid excretion into feces when subjects took high-lipid diet.

Effect of Resistant Maltodextrin on Digestion and Absorption of Lipids

“…It has been reported that lipid excretion in feces increased by the administration of oolong tea polyphenols. 16) In the polyphenol study, fecal lipid concentration (estimated from the reported data) seemed to stay in similar levels as shown in our current study, suggesting a possibility that there may be some upper limit for fecal lipid concentration while keeping normal fecal shape and conditions.…”

“…Polyphenols have been reported to suppress postprandial elevation of triacylglycerol by promoting lipid excretion into feces, 15,16) so we considered that RMD would also have a similar function; promotion of lipid excretion. We conducted the animal and human experiments to confirm the effect of RMD on the lipid excretion into feces.…”

Suppression of Postprandial Hypertriglyceridemia in Rats and Mice by Oolong Tea Polymerized Polyphenols

“…Moreover, we determined in a human study that polyphenol-enriched oolong tea increased lipid excretion into the feces when subjects took a high lipid diet. 25) These findings confirm that oolong tea and OTPP inhibited dietary fat absorption in the intestine by inhibiting pancreatic lipase activity.…”

The role of lipid and carbohydrate digestive enzyme inhibitors in the management of obesity: a review of current and emerging therapeutic agents

“…176 Some published data suggest that extract-induced fecal lipid excretion is associated with reductions in weight gain and changes in TG metabolism, 97,177 while other studies report no significant correlations. 178 The lack of effects found in some studies could be due to compensatory increases in lipase secretion similar to those seen in studies on condensed tannins in rats.…”