Polypharmacy: Something more than just numbers

Reina, Encarnación Blanco; Valdellós, Jenifer

doi:10.1016/j.medcle.2019.02.027

Cited by 2 publications

(1 citation statement)

References 20 publications

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“…The negative consequences of polypharmacy for patients are numerous and can be divided into clinical, such as increased physical and cognitive impairment, frailty, hospitalizations, and mortality [ 10 , 11 , 12 , 13 ]; and pharmacological, leading to a greater likelihood of adverse drug reactions (ADRs), drug duplications, therapeutic cascades, and adherence problems [ 14 , 15 , 16 ].…”

Section: Introductionmentioning

confidence: 99%

Feasibility study of a clinical decision support system for polymedicated patients in primary care

Manzanet

Fico

Merino‐Barbancho

et al. 2023

Healthcare Tech Letters

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Age‐related changes in pharmacokinetics and pharmacodynamics, multimorbidity, frailty, and cognitive impairment represent challenges for drug treatments. Moreover, older adults are commonly exposed to polypharmacy, leading to increased risk of drug interactions and related adverse events, and higher costs for the healthcare systems. Thus, the complex task of prescribing medications to older polymedicated patients encourages the use of Clinical Decision Support Systems (CDSS). This paper evaluates the CDSS miniQ for identifying potentially inappropriate prescribing in poly‐medicated older adults and assesses the usability and acceptability of the system in health care professionals, patients, and caregivers. The results of the study demonstrate that the miniQ system was useful for Primary Care physicians in significantly improving prescription, thereby reducing potentially inappropriate medication prescriptions for elderly patients. Additionally, the system was found to be beneficial for patients and their caregivers in understanding their medications, as well as usable and acceptable among healthcare professionals, patients, and caregivers, highlighting the potential to improve the prescription process and reduce errors, and enhancing the quality of care for elderly patients with polypharmacy, reducing adverse drug events, and improving medication management.

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Section: Introductionmentioning

confidence: 99%

Feasibility study of a clinical decision support system for polymedicated patients in primary care

Manzanet

Fico

Merino‐Barbancho

et al. 2023

Healthcare Tech Letters

View full text Add to dashboard Cite

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Polypharmacy in patients with chronic-degenerative diseases in a remote community, Puebla- México.

Sánchez-Hernádez

Morales-Pérez²,

Osorio-Espinoza³

2022

Rev. Médica Risaralda

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Objective: To determine if patients with chronic degenerative diseases between 50-90 years of age have polypharmacy and drug interactions, at the Huajoyuca Health Center of Palacios, between June 2018-June 2019. Methodology: A descriptive, observational, non-experimental, statistical, retrospective, cross-sectional, unicentric research was carried out. The sample consisted of 56 files according to the inclusion criteria. Data were analyzed according to descriptive statistics and frequency histograms. Results: The mean age is 67.11 ± 9.6 years. There was a higher prevalence of polypharmacy in the 60-69 age range. Due to excessive medication consumption, women make up 82 percent of those affected. Patients with chronic-degenerative disorders are the most likely to have polypharmacy, and those with comorbid conditions even more, it was observed that the consumption and frequency of medications per patient is 4.08 ± 1.56 medications. The top drugs consumed daily are metformin (17.41%), hydrochlorothiazide (12.05%), B vitamin, acetylsalicylic acid glibenclamide with (11.16%), losartan (8.03%), enalapril (6.69%), captopril (4.91 %). 38 patients with (68%) had minor polypharmacy, 17 patients with (30%) had major polypharmacy, and 1 patient with (2%), had excess polypharmacy. Conclusion: In order from highest to lowest, patients with type 2 diabetes mellitus have minor polypharmacy, unlike hypertensive and dyslipidemic patients. The gender most affected by polypharmacy is the female with 82% vs. 18% the male gender of the population studied.

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Polypharmacy: Something more than just numbers

Cited by 2 publications

References 20 publications

Feasibility study of a clinical decision support system for polymedicated patients in primary care

Feasibility study of a clinical decision support system for polymedicated patients in primary care

Polypharmacy in patients with chronic-degenerative diseases in a remote community, Puebla- México.

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