Abstract:Drug interactions are a critical problem in clinical pharmacology and daily clinical practice. Physicians often face the need to prescribe a combination of two or more drugs (polypharmacy), especially when treating patients with several comorbidities. In some combinations, drugs, being chemically active substances, can enter into multi-drug interactions often with clinically significant adverse effects and/or reduction of therapy effectiveness, increasing the cost of treatment. Potential multi-drug interaction… Show more
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