Polyp prevalence at colonoscopy among Nigerians: A prospective observational study

Abstract

We conclude that polyps are probably not as rare among black Africans especially when they are above 50 years. Our histopathological finding of adenomatous change in a good proportion of the detected polyps show that they are likely to be associated with CRCs in our compatriots and as such we would recommend a routine screening colonoscopy for Nigerians aged 50 and above.

A Clinicopathological Review of Colonic Polyps in a Tertiary Hospital in North Central Nigeria

“…Some of the reported PDR from the latter include 35.5%, 45.8%, and 49.0% from France, Spain, and the United States, respectively [24][25][26]. Our ADR of 4.8% is the same as that obtained in Lagos, lower than the 6.8% obtained in Ile-Ife but higher than 2.9% obtained in Ghana [10,11,17]. These ADRs from African countries are, however, much lower than the 17.7%, 19.4%, and 31.0% obtained in France, Germany, and the United States, respectively [24,26,27].…”

“…obtained by Alatise et al in Ile-Ife, South Western, Nigeria [11]. In Ado-Ekiti, Southwestern region of Nigeria, the prevalence of polyps was 14.7% among patients with lower GI bleeding.…”

“…Nigeria and other sub-Saharan African countries suggest that they may not be as rare as previously reported though the prevalence rates are still relatively low when compared to the rates reported among Caucasians and Asians [10][11][12][13][14][15][16][17]. Over a period May, 2012 [14].…”

“…It was estimated that 30% of the Western population have colonic polyps, whereas lower rates (10-15%) were noted in Africa [8,9]. Recent studies in Nigeria and other sub-Saharan African countries have reported different prevalence rates of colonic polyps that appear to suggest that their occurrence in these countries may not be rare as previously noted [10][11][12][13][14][15][16][17]. Results from previous studies have also shown that colonic polyps are more common in men than in women and increase in frequency with increasing age in most of these studies.…”

Endoscopic Improvement of the Adenoma Detection Rate during Colonoscopy - Where Do We Stand in 2015?

“…Data from the United States [10] endorse European and Asian experiences and stress the importance of raising ADR in patients above 50 years of age. Data from Africa are difficult to obtain (just like it is in other developing countries), but newly published data display the same increase of ADR in an African population [11] over and above the 5th decade of life. In conclusion, the positive correlation of higher adenoma incidence with subsequently higher ADRs and higher age is a global phenomenon.…”