Polyoxometalates as components of supramolecular assemblies

Stuckart, Maria; Monakhov, Kirill Yu.

doi:10.1039/c9sc00979e

Cited by 117 publications

(91 citation statements)

References 125 publications

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“…Thus, POMs exhibit outstanding physical, chemical, and biochemical properties that remain to be completely understood and applied. Due to these properties, POMs are studied in environmental, chemical, and industrial fields, particularly in the areas of catalysis, corrosion prevention, smart glasses, and macromolecular crystallography, as well as in biology, such as for cancer treatment, bacterial infection, and diabetes, among others [1][2][3][4][5][6]. Although the number of POM studies with anticancer effects is increasing, their mechanisms of action in each type of cancer cell are still far from being understood [3].…”

Section: Introductionmentioning

confidence: 99%

The Aquaporin-3-Inhibiting Potential of Polyoxotungstates

Pimpão

Silva

Mósca

et al. 2020

IJMS

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Polyoxometalates (POMs) are of increasing interest due to their proven anticancer activities. Aquaporins (AQPs) were found to be overexpressed in tumors bringing particular attention to their inhibitors as anticancer drugs. Herein, we report for the first time the ability of polyoxotungstates (POTs), such as of Wells–Dawson P2W18, P2W12, and P2W15, and Preyssler P5W30 structures, to affect aquaporin-3 (AQP3) activity and impair melanoma cell migration. The tested POTs were revealed to inhibit AQP3 function with different effects, with P2W18, P2W12, and P5W30 being the most potent (50% inhibitory concentration (IC50) = 0.8, 2.8, and 3.2 µM), and P2W15 being the weakest (IC50 > 100 µM). The selectivity of P2W18 toward AQP3 was confirmed in yeast cells transformed with human aquaglyceroporins. The effect of P2W12 and P2W18 on melanoma cells that highly express AQP3 revealed an impairment of cell migration between 55% and 65% after 24 h, indicating that the anticancer properties of these compounds may in part be due to the blockage of AQP3-mediated permeability. Altogether, our data revealed that P2W18 strongly affects AQP3 activity and cancer cell growth, unveiling its potential as an anticancer drug against tumors where AQP3 is highly expressed.

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Section: Introductionmentioning

confidence: 99%

The Aquaporin-3-Inhibiting Potential of Polyoxotungstates

Pimpão

Silva

Mósca

et al. 2020

IJMS

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“…Their structural and chemical diversity can provide many attractivef unctionsa nd thusf acilitatearange of significant applications in catalysis, medicine, biology,e nergy,m aterials science and so forth. [3][4][5][6][7][8][9][10] More significantly,P OM clusters can be additionally functionalised with organic or biological molecules to further broaden the scope of their applicability. [11,12] Polymers are aw idely used class of materials because of their excellentp erformance and processability.T he development of advanced functionalp olymer materials is as traightforward strategy for meeting the needs of technological progress.…”

Section: Introductionmentioning

confidence: 99%

Twining Poly(polyoxometalate) Chains into Nanoropes

Zhang

Miao

Ren

et al. 2019

Chemistry A European J

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Organic polymers and inorganic clusters belong to two different disciplines and have completely different properties and structures. When a cluster is attached to the backbone of a polymer as a pendant, the resultant hybrid polymers (polyclusters) exhibit unique behaviours totally different from those of conventional polymers owing to the nanoscale size of the cluster and its particular interactions. Herein, the aggregation of a poly(polyoxometalate)—a polynorbornene backbone with inorganic polyoxometalate cluster pendants—upon addition of a non‐solvent to its dilute solution is reported. A three‐dimensional network of tangled and snake‐like nanothreads was observed. Direct visualisation of individual nanoscale clusters enabled identification of single chains within the nanothreads. These observations suggest that during the process of aggregation, the hybrid polymer forms curved or extended chains as a consequence of an armouring effect in which the collapsed cluster pendants wrap around the backbone. The collapse occurs because they become less soluble in the solvent/non‐solvent mixture. The extended chains then become entwined and form nanoropes consisting of multiple chains wound around each other. This study provides a deeper understanding of the nature of polyclusters and should also prove useful for their future development and application.

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“…Therefore, increasing their performance in SCs has become an important research direction. Numerous researchers have started developing composites based on POMs and high conductivity materials . In particular, the design and preparation of POMOFs had evolved into an effective strategy for achieving good dispersion of POMs at the molecular level and exposing more accessible active sites, thereby greatly increasing the specific surface area and pores of POMs.…”

Section: Introductionmentioning

confidence: 99%

“…Numerous researchers have startedd eveloping composites based on POMs and high conductivity materials. [29] In particular, the design and preparation of POMOFs had evolvedi nto an effective strategy for achieving good dispersion of POMs at the molecular level and exposing more accessible active sites, therebyg reatlyi ncreasingt he specific surfacea rea and pores of POMs. In 2017, Ma et al [30] reported the Keggin-based 3D coordinationp olymer,w hich was used as the electrode material, and showed that it had the capacitance of 206 Fg À1 and 81.7 %r etention after 1000 cycles.…”

Section: Introductionmentioning

confidence: 99%

A Facile Grinding Method for the Synthesis of 3D Ag Metal–Organic Frameworks (MOFs) Containing Ag₆Mo₇O₂₄ for High‐Performance Supercapacitors

Zhao

Gong

Wang

et al. 2020

Chemistry A European J

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Successful synthesis of three kinds of dynamically stable compounds by a simple grinding method is reported, giving Ag6Mo7O24, Ag‐BTC (Ag‐MOF, BTC=benzene‐1,3,5‐tricarboxylic acid), and {Ag6Mo7O24}@Ag‐MOF metal–organic frameworks (MOFs). According to the electrochemical dynamic analysis, these materials have pseudocapacitor behavior and high capacitance. The unique nanorod structure of {Ag6Mo7O24}@Ag‐MOF provides more active sites, faster ion/electron transfer, and electrolyte diffusion pathways, resulting in excellent specific capacitance (971 F g−1) higher than the other compounds. {Ag6Mo7O24}@Ag‐MOF (glassy carbon electrode) also has an excellent rate ability (60.1 %) and long cycle stability (98 % retention after 5000 cycles). In addition, the fully symmetrical button battery (with nickel foam as the current collector) fabricated with {Ag6Mo7O24}@Ag‐MOF delivers an energy density of 11.1 Wh kg−1 at 600.1 Wh kg−1 coupled with excellent cycling stability (86.4 %) at 1.2 V. These results demonstrate a new simple grinding method to prepare polyoxometalate‐based metal–organic frameworks (POMOFs) for high‐performance materials.

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Polyoxometalates as components of supramolecular assemblies

Abstract: The non-covalent interactions between polyoxometalates and inorganic- and organic-based moieties give rise to functional nanoassemblies with diverse potential in applied science.

Cited by 117 publications

References 125 publications

The Aquaporin-3-Inhibiting Potential of Polyoxotungstates

The Aquaporin-3-Inhibiting Potential of Polyoxotungstates

Twining Poly(polyoxometalate) Chains into Nanoropes

A Facile Grinding Method for the Synthesis of 3D Ag Metal–Organic Frameworks (MOFs) Containing Ag₆Mo₇O₂₄ for High‐Performance Supercapacitors

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Polyoxometalates as components of supramolecular assemblies

Abstract: The non-covalent interactions between polyoxometalates and inorganic- and organic-based moieties give rise to functional nanoassemblies with diverse potential in applied science.

Cited by 117 publications

References 125 publications

The Aquaporin-3-Inhibiting Potential of Polyoxotungstates

The Aquaporin-3-Inhibiting Potential of Polyoxotungstates

Twining Poly(polyoxometalate) Chains into Nanoropes

A Facile Grinding Method for the Synthesis of 3D Ag Metal–Organic Frameworks (MOFs) Containing Ag6Mo7O24 for High‐Performance Supercapacitors

Contact Info

Product

Resources

About

A Facile Grinding Method for the Synthesis of 3D Ag Metal–Organic Frameworks (MOFs) Containing Ag₆Mo₇O₂₄ for High‐Performance Supercapacitors