Polyoxometalate–covalent organic framework hybrid materials for pH-responsive photothermal tumor therapy

Wang, Wenxin; Song, Yuting; Chen, Jiayi; Wang, Jiawei; Song, Yan; Ni, Jiatong; Tang, Minglu; Zhao, Junge; Sun, Yuan; Sun, Tiedong; Peng, Jinsong

doi:10.1039/d1tb02255e

Cited by 23 publications

(11 citation statements)

References 56 publications

(52 reference statements)

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“…The resulting HPB@COF platform exhibits ideal biocompatibility, pH-responsive release properties, and high tumor-suppressive efficiency for PTT, which inhibit tumor growth. A safer and more effective COFbased nano-delivery platform is fabricated for future pH-responsive photothermal therapy [38].…”

Section: Cofs Used For Photothermal Therapy (Ptt)mentioning

confidence: 99%

“…Therefore, effective cancer treatment by mild photothermal therapy at low temperatures is vital. Sun et al designed nano-agents (a) Synthesis process of HPB@COF; Mechanism by which HPB@COF protects normal cells and kills cancer cells [38]. Reproduced with permission from ref.…”

Section: Cofs Used For Photothermal Therapy (Ptt)mentioning

confidence: 99%

Section: Cofs Used For Photothermal Therapy (Ptt)mentioning

confidence: 99%

“…Figure 3. (a) Synthesis process of HPB@COF; Mechanism by which HPB@COF protects normal cells and kills cancer cells[38]. Reproduced with permission from ref [38]…”

mentioning

confidence: 99%

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Applications of Covalent Organic Frameworks (COFs) in Oncotherapy

Gao¹

2023

Covalent Organic Frameworks

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Covalent organic frameworks (COFs) are emerging organic crystalline polymer materials, which are formed by reversible condensation reactions between lightweight molecular fragments. They have excellent properties such as low density, good porosity and crystallinity, and high thermal stability. These materials are biodegradable due to the reversible condensation process between the monomers. Compared with another widely studied material with metal-organic frameworks, COFs have no additional toxicity caused by introducing metal ions. Therefore, a high potential exists in biomedicine. The chapter aimed to introduce the application of biomaterial COFs in oncotherapy and identify the specific advantages of different types of COFs for specific biomedical applications.

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Section: Cofs Used For Photothermal Therapy (Ptt)mentioning

confidence: 99%

Section: Cofs Used For Photothermal Therapy (Ptt)mentioning

confidence: 99%

Section: Cofs Used For Photothermal Therapy (Ptt)mentioning

confidence: 99%

“…Figure 3. (a) Synthesis process of HPB@COF; Mechanism by which HPB@COF protects normal cells and kills cancer cells[38]. Reproduced with permission from ref [38]…”

mentioning

confidence: 99%

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Applications of Covalent Organic Frameworks (COFs) in Oncotherapy

Gao¹

2023

Covalent Organic Frameworks

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“…Some works have been reported on the application of heteropoly blue (HPB) in the field of photothermal conversion, such as photothermal therapy [14][15][16][17] and photothermal catalysis. [18] In 2019, Wang et al applied the prepared CuOÀ PMo 12 ultrathin nanosheets for the first time to study the performance of photothermal water evaporation.…”

Section: Introductionmentioning

confidence: 99%

Heteropoly Blue/Carbon Nanotubes Nanocomposites as High‐Performance Photothermal Conversion Materials

Wang

Zhao

Xiao

et al. 2023

Chemistry A European J

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To realize the direct and full use of the widely distributed solar energy, developing novel materials with superb photothermal conversion capability is essential. Although heteropoly blue has intrinsic outstanding solar absorption and photothermal conversion properties, its spectral absorption in the infrared region is weak. Here, composites of heteropoly blue and carbon nanotubes (HPB/CNTs) are synthesized depending on electrostatic interactions by facile microwave sonication and freeze‐drying. The doped CNTs can dramatically improve the spectral absorption performance of HPB ontology in the infrared region. As a result, the light absorption of the optimized HPB/CNTs (20 %) reaches more than 95 % in the range of 200–2400 nm, showing promising prospects as high‐performance photothermal conversion material in the applications of solar desalination and wastewater treatment.

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Covalent Organic Frameworks: Opportunities for Rational Materials Design in Cancer Therapy

Zhou,

Guan,

Dong

2023

Angewandte Chemie

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Nanomedicines are extensively used in cancer therapy. Covalent organic frameworks (COFs) are crystalline organic porous materials with several benefits for cancer therapy, including porosity, design flexibility, functionalizability, and biocompatibility. This review examines the use of COFs in cancer therapy from the perspective of reticular chemistry and function‐oriented materials design. First, the modification sites and functionalization methods of COFs are discussed, followed by their potential as multifunctional nanoplatforms for tumor targeting, imaging, and therapy by integrating functional components. Finally, some challenges in the clinical translation of COFs are presented with the hope of promoting the development of COF‐based anticancer nanomedicines and bringing COFs closer to clinical trials.

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Polyoxometalate–covalent organic framework hybrid materials for pH-responsive photothermal tumor therapy

Abstract: Photothermal therapy (PTT) has become one of the most effective methods for tumor treatment. With the development of medicine, studies focusing primarily on the therapeutic and diagnostic agents with desirable...

Cited by 23 publications

References 56 publications

Applications of Covalent Organic Frameworks (COFs) in Oncotherapy

Applications of Covalent Organic Frameworks (COFs) in Oncotherapy

Heteropoly Blue/Carbon Nanotubes Nanocomposites as High‐Performance Photothermal Conversion Materials

Covalent Organic Frameworks: Opportunities for Rational Materials Design in Cancer Therapy

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