Polyostotic fibrous dysplasia with severe pathologic compression fracture of L2

Abstract

A case of a progressive pathologic compression fracture of L2 due to polyostotic fibrous dysplasia is presented. Such unusually severe involvement, requiring decompression and surgical fusion, in the absence of significant recent or remote trauma, has not previously been reported.

Spinal polyostotic fibrous dysplasia in two adults: Does only biopsy unravel the mystery?

“…Though fracture is a common complication of FD of extremities, it is rarely noted in spine. [1213] The fracture in our patient could be due to the multiple falls he sustained.…”

“…Successful vertebroplasty has been performed in cases of FD with severe kyphosis and neurological involvement due to compression by expanding FD lesions or fracture. [1213]…”

Isolated polyostotic fibrous dysplasia of the spine: A diagnostic challenge

“…The lesions may present with minor symptoms and the clinical signs and symptoms are disproportionate to the imaging findings which are quite advanced. Spinal cord compression is quite rare [8]. The discrepancy in the clinical and imaging findings is quite helpful in arriving at a clinico-radiological diagnosis.…”

“…Fibrous dysplasia affecting the vertebrae is very unusual [1,3,4,7,8]. Dahlin and Unni found only two cases of vertebral involvement out of 418 cases reviewed [3].…”

False Positive FDG PET/CT Resulting from Fibrous Dysplasia of the Bone in the Work-Up of a Patient with Bladder Cancer: Case Report and Review of the Literature

“…FDB usually has sclerotic margins on CT scans and may have a matrix of uniform density (17). Additionally, CT can reveal areas of cortical breakthrough usually associated with cortical thinning and bone expansion that are not appreciated occasionally on radiographic reviews (17, 20-23). Distinction between FDB, adamantinoma and ossifying fibroma can be difficult and FDB can appear very similar to adamantinoma (13, 14, 16, 24-26).…”