Polyomavirus Nephropathy in the Native Kidneys of an Unrelated Cord Blood Transplant Recipient Followed by A Disseminated Polyomavirus Infection

Polyomaviruses KI and WU in Immunocompromised Patients with Respiratory Disease

“…Considering the seemingly higher prevalence of KIPyV in our population (8%), immunocompromised patients may be more susceptible to this PyV, as they are to JC and BK viruses (13)(14)(15). Results from previous reports suggest a similar frequency of both KIPyV and WUPyV infections being found in respiratory specimens, ranging from 1% to 3%.…”

Polyomavirus BK infection in blood and marrow transplant recipients

“…27 However, in recent years, several cases of BK nephritis in the native kidneys of BMT recipients, not always accompanied by hemorrhagic cystitis, have been reported. [67][68][69][70] A report of bilateral ureteral obstruction possibly related to ureteritis caused by BK virus infection in a BMT recipient has also been reported. 71 In recent years, clinical manifestations of BK virus infection in organ systems outside of the genitourinary tract have been reported 14 (Table 5).…”

Acute renal failure associated with systemic polyoma BK virus activation in a patient with peripheral T-cell lymphoma

“…The prevalence of PVAN after kidney transplantation has been reported to be 1-7%, and persistence of PVAN was associated with irreversible kidney allograft failure in 10-100% [1]. BKV viruria occurs in about 50% of HCT recipients and is associated with hemorrhagic cystitis and PVAN [1][2][3]. On the other hand, BKV-associated nephropathy as a complication after conventional chemotherapy is very rare, and only a few cases have been reported.…”

“…Latent BKV can be reactivated in immunosuppressed patients and cause diverse urinary tract disorders such as hemorrhagic cystitis, ureteric stenosis, renal dysfunction, and even multi-organ failure [1]. Among these entities, polyoma virus-associated nephropathy (PVAN) is a well-known complication in the setting of profound immunosuppression related to renal transplantation and hematopoietic stem cell transplantation (HCT) [1][2][3]. However, it has been rarely described as a complication during the course of conventional chemotherapy.…”