“…Kitamoto and Gruen (1976) that polyol and trehalose are synthesized in mycelia and translocated into the fruit bodies, as reported in a number of studies on the polyol metabolism in relation to fruit-body formation of mushrooms such as Agaricus campestris Linnaeus (Edmundowicz and Wriston 1963), Schizophyllum commune (Niederpruem et al 1965), Agaricus bisporus (Ruffner et al 1978), Favolus arcularius (Fr.) Ames, 69B/ ATCC 24461 (Kitamoto et al 1978), Coprinus phlyctidosporus Romagnesi (Kitamoto et al 1999), and F. velutipes (Kitamoto et al 2000). Taken together, this investigation provides new enzymatic evidence for the occurrence of GLOX-gluconeogenesis pathway in the mycelium, which might be supported by glutamate synthesis during the fruit-body formation of F. velutipes.…”