Polymyositis has minimal effect on primary total knee or hip arthroplasty outcomes

Singh, Jasvinder A.; Cleveland, Jeanette N.

doi:10.1007/s10067-019-04877-8

Cited by 2 publications

(1 citation statement)

References 23 publications

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“…The NIS has been reliably used to address some important clinical knowledge gaps in patients with IIM. Several studies on DM and PM based on the NIS database have shown a high rate of infection, cardiopulmonary and rheumatological comorbidities, and increased resource utilization through imaging studies (10)(11)(12)(13). However, large national scale studies on IBM are lacking.…”

Section: Discussionmentioning

confidence: 99%

In-patient comorbidities in inclusion body myositis: a United States national in-patient sample-based study

Anthony

Ding²,

Roy

2022

Clinical and Experimental Rheumatology

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ObjectivesInclusion body myositis (IBM) is the most common idiopathic inflammatory myopathy (IIM) above the age of 50 with a distinct clinical phenotype of progressive, painless, asymmetric weakness predominantly involving the long finger flexors and quadriceps. In this study, we compared comorbidities in IBM with other IIMs (i.e., dermatomyositis (DM) and polymyositis (PM)) from the United States National Inpatient Sample Database. Methods We identified patients with a primary diagnosis of IBM or IIM from the National Inpatient Sample (NIS) from 2012 to 2018.We then compared the rate of common inpatient comorbidities between the IBM and IIM. ResultsThere were 18,819 admissions for patients with either IBM or IIM. IBM patients were older (72.9±10.7 years vs. 59.3±18.4 years for IIM, p<0.001), predominantly men (65.0% vs. 31.2% for IIM, p<0.001), and White Caucasians (82.5% vs. 58.4% for IIM, p<0.001). IBM patients had significantly more frequent events of aspiration pneumonia, atrial fibrillation, falls, and sepsis. The rate of PEG tube placement was also significantly higher. When performing multivariable logistic regression, we found that IBM is a risk factor for aspiration pneumonia (OR 3.03), PEG tube placement (OR 2.91), falls (OR 2.05), and sepsis (OR 1.30) but not for significant cardiovascular events. Conclusion IBM increases a patient's risk for dysphagia, falls, and infection as compared to other IIM patients. Further population-based studies are warranted to better elucidate the impact of these comorbidities in patients with IBM.

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Section: Discussionmentioning

confidence: 99%