Polymyalgia Rheumatica and Giant Cell Arteritis

Buttgereit, Frank; Dejaco, Christian; Matteson, Eric L.; Dasgupta, Bhaskar

doi:10.1001/jama.2016.5444

Cited by 393 publications

(311 citation statements)

References 77 publications

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“…Prognostic tools for treatment stratification are crucial. Methotrexate (MTX) has been studied in PMR but evidence only allows individualized use in patients at risk of relapse, exposed to prolonged GC therapy, and experiencing GC-related adverse events (17). However, the effect of MTX is modest and RCTs of other synthetic DMARDs such as leflunomide are urgently needed.…”

Section: N the Need Of An Optimal Framework For The Development Of Efmentioning

confidence: 99%

Perspectives and unmet needs in polymyalgia rheumatica. Providing the fundamental framework for the development of new treatment regimes in polymyalgia rheumatica

Nielsen

Dasgupta

2018

Reumatismo

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SUMMARYPolymyalgia rheumatica is effectively treated with glucocorticoids. However, glucocorticoid treatment can cause numerous and potentially serious side effects. Therefore, lowest effective dose and shortest duration to control disease is aimed for and glucocorticoid-sparing treatments are needed. Nevertheless, development of treatment regimens in PMR has been hampered by the lack of reliable classification criteria and evidence-based outcome measures. In this editorial, we discuss the need for valid classification criteria in PMR, the strengths and limitations of the ACR/EULAR 2012 provisional classification criteria for PMR and the need of validation and possible refining of the criteria.

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Section: N the Need Of An Optimal Framework For The Development Of Efmentioning

confidence: 99%

Perspectives and unmet needs in polymyalgia rheumatica. Providing the fundamental framework for the development of new treatment regimes in polymyalgia rheumatica

Nielsen

Dasgupta

2018

Reumatismo

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“…Nuclear medicine studies such as positron emission tomography (PET) with fluorodeoxyglucose (FDG) have been used. 9 Although cost and radiation limit its use in routine practice, PET can identify important differential diagnoses such as infection and malignancy, and characteristic features of polymyalgia rheumatica may also be seen.…”

Section: Articlementioning

confidence: 99%

Prescribing for polymyalgia rheumatica

2018

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“…Giant cell arteritis (GCA), or temporal arteritis, is a chronic vasculitis of large-and medium-sized vessels, that affects, almost exclusively, the elderly population, with mean age of presentation of 65 years or more. 36 Persistent headache, either unilateral or bilateral, with jaw claudication are hallmark symptoms, while patients may also present with fever and even acute vision loss. 36 Elevated inflammatory markers, erythrocyte sedimentation rate (ESR) or C-reactive protein (CRP), can be valuable tools in diagnosis, but negative values do not rule out GCA.…”

Section: Infectious/inflammatorymentioning

confidence: 99%

“…36 Persistent headache, either unilateral or bilateral, with jaw claudication are hallmark symptoms, while patients may also present with fever and even acute vision loss. 36 Elevated inflammatory markers, erythrocyte sedimentation rate (ESR) or C-reactive protein (CRP), can be valuable tools in diagnosis, but negative values do not rule out GCA. 35 Diagnosis may be aided by neuroimaging, either ultrasonography or MRI, and a temporal artery biopsy may also be done for a definitive diagnosis.…”

Section: Infectious/inflammatorymentioning

confidence: 99%

Headache in the Emergency Room

Kahkeshani¹,

Sheikh²

2017

US Neurology

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Headache is seen in the emergency room (ER) on a daily basis and is a vague symptom, which can be a part of many different types of conditions and diseases. Although most people who come to the ER will have a benign headache, it is important to make sure that dangerous causes of headache are ruled out. There are a number of features that may alert someone to a secondary cause of headache. This article highlights two specific secondary headache syndromes, including carotid dissection and reversible cerebral vasoconstriction syndrome. It also broadly points out other possible causes of secondary headache. The last section focuses on a common primary headache that presents to the ER, migraine and its treatment.

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Polymyalgia Rheumatica and Giant Cell Arteritis

Cited by 393 publications

References 77 publications

Perspectives and unmet needs in polymyalgia rheumatica. Providing the fundamental framework for the development of new treatment regimes in polymyalgia rheumatica

Perspectives and unmet needs in polymyalgia rheumatica. Providing the fundamental framework for the development of new treatment regimes in polymyalgia rheumatica

Prescribing for polymyalgia rheumatica

Headache in the Emergency Room

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