Polymorphous light eruption

Naleway, Allison L.

doi:10.1046/j.1365-4362.2002.01467.x

Cited by 27 publications

(32 citation statements)

References 34 publications

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“…17 According to Morrison, the age of onset varied between 20-40 years and according to Naleway, mean age at onset of the disease ranged from 26 to 37 years. 15,18 From these studies, it was clear that the age of onset varies considerably, although there seems to be a definite tendency for this disorder to be common in 2nd to 3rd decade which is seen in our study.…”

Section: Age Of Onset Distributionsupporting

confidence: 48%

A clinico-epidemiological study of polymorphic light eruption in a tertiary care centre in Salem: a region of South India

et al. 2017

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Introduction: Polymorphic light eruption (PMLE) is an acquired photodermatosis characterized by a polymorphic eruption ranging from papulovesicular lesions to large plaques. The prevalence of PMLE varies from 5% to 15% in various studies across the world and in India it is 0.56%.Objective: The present study was conducted to study the clinical pattern and to assess the epidemiological aspects of polymorphic light eruption.Material and Method: A cross sectional prospective study was conducted in Dermatology OPD between April 2015 and June 2016. A total of 100 patients with symptoms and signs of PMLE were included in the study. Data were coded and analyzed.Results: Majority of the cases in our study were in the age group of 21 - 30 years (36%). It was more common in females (82%) when compared with males (18%). Occupation of most of the patients (29%) was farmers in our study population. Positive family history of PMLE was seen in 11% of the study population. The commonest form was the papular type (46%) and the second most common type was plaque type (17%). Regarding the distribution of lesions, about 51% of our study subjects had polymorphic lesions confined to only one area of their body mostly forearm (25%) followed by face (12%).Conclusion: The prevalence of PMLE was 1.34% in our study population. Pruritus was the presenting complaint in most of the cases and the rash was mainly seen in areas exposed to sunlight.

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Section: Age Of Onset Distributionsupporting

confidence: 48%

A clinico-epidemiological study of polymorphic light eruption in a tertiary care centre in Salem: a region of South India

et al. 2017

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“…1 Women are affected two to three times more often than men and the disease is showing some familial predisposition. 1,2,5,6 PLE is assumed to represent a type IV hypersensitivity reaction to a UV-induced (UVA, UVB or both types of radiation) cutaneous antigen. 1 PLE is expected to be further influenced by genetic, photobiological and biochemical factors.…”

Section: Introductionmentioning

confidence: 99%

GSTM1, GSTT1 and GSTP1 gene polymorphism in polymorphous light eruption

Zirbs

Pürner

Buters

et al. 2012

Acad Dermatol Venereol

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“…If untreated, lesions subside within a few days if further sun exposure is avoided. The eruption is more severe following the first major exposure to sunlight in spring or early summer, and, after repetitive exposures, many individuals experience a hardening effect . The pathogenesis of PLE remains to be clarified, but an autoimmune reaction to unknown photoinduced antigens seems to play a major role as PLE patients are resistant to UV‐induced immunosuppression .…”

Section: Introductionmentioning

confidence: 99%