“…[42][43][44][45] However, other studies concerning the clinical significance of the TGF- 1 polymorphisms rendered contradictory findings. 2,[46][47][48][49][50][51] Recent studies failed to present a genetic association in implant loss. 52,53 Wilson and Nunn 52 assessed the impact of composite genotype status to interleukin-1 (IL-1) on implant retention among patients who were smokers or nonsmokers.…”