Abstract:The aim of our research was to study the association of the-675 4G/5G (rs1799889) SNP of the SERPINE1 (PAI-1) gene and the Arg353Gln G>A (rs6046) SNP of the F7 gene with metabolic syndrome (MetS) in the Yakuts with COPD. Methods and Results: A molecular-genetic examination was conducted in 200 COPD patients of Yakut ethnicity. The main group (MG) consisted of 100 COPD patients with MetS, the comparison group (CG) included 100 COPD patients without MetS. The distribution of genotypes of studied SNPs was in Hard… Show more
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