Polymorphisms in VEGF and KDR genes in the development of endometriosis: a systematic review

Cardoso, Jéssica Vilarinho; Machado, Daniel Escorsim; Ferrari, Renato; Silva, Mayara Calixto da; Berardo, Plínio Tostes; Perini, Jamila Alessandra

doi:10.1590/1806-93042016000300002

Cited by 3 publications

(1 citation statement)

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“…2 It is estimated that 10% of women of reproductive age, 30 to 50% of infertile women and 3 to 5% of postmenopausal women may be diagnosed with EDM. 3 Symptoms of the disease are variable and nonspecific, mostly associated with dysmenorrhea, dyspareunia, CPP, infertility, and urinary or intestinal disorders, making diagnosis difficult. 4 The main symptoms are: pain and infertility, with some women suffering extreme pain (CPP).…”

Section: Introductionmentioning

confidence: 99%

Analysis of the influence of endometriosis on quality of life

et al. 2022

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Introduction: Endometriosis is a disorder that can significantly affect quality of life (QOL) and interfere in biological, psychological, social, marital and family aspects. Objective: To analyze the influence of endometriosis on the QOL of women diagnosed with the disease. Methods: The study was carried out from March to April 2018, with 10 volunteers from the Santa Casa de Misericórdia do Pará Foundation, with a clinical diagnosis of endometriosis. The Portuguese version of the endometriosis health profile questionnaire (EHP-30) was applied in order to assess QOL in women with this pathology. Results: The sociodemographic results revealed a predominance of women aged between 29 and 55 years, most of whom were married (6) and high school graduates (5). Seven of the ten volunteers had previous pregnancies. Of the aspects evaluated in the EHP-30, 79% of the items associated with pelvic pain in the core questionnaire were present in the participants. In other questionnaires, sexual life (82%) was the most affected index, followed by professional life (70%) and infertility (58.82%). Conclusion: The aspects of QOL most impacted by pelvic pain associated with endometriosis in the women evaluated were sexuality and professional life, leading to biopsychosocial trauma.

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Section: Introductionmentioning

confidence: 99%