Polymorphism of rs599839 in the PSRC1 gene is associated with coronary artery disease in an Iranian population
Golnaz Houshmand,
Mohammad Javad Alemzadeh-Ansari,
Saeideh Mazloumzadeh
et al.
Abstract:Introduction: Coronary artery disease (CAD) is the leading health complication worldwide because of its high prevalence and mortality. The association between CAD susceptibility and the rs599839 (C/T) polymorphism in the human proline and serine-rich coiled-coil (PSRC1) was reported in a genome-wide association study. To validate this association, we performed this case-control study to genotype the 1p13.3 (rs599839) locus in a sample of the Iranian population with CAD (stenosis≥70% in≥1 coronary artery). Meth… Show more
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