Background:This article presents the design of PROFILe, a study
investigating which (bio)medical and non-(bio)medical patient characteristics
should guide more tailored chronic care. Based on this insight, the project aims
to develop and validate ‘patient profiles’ that can be used in
practice to determine optimal treatment strategies for subgroups of chronically
ill with similar healthcare needs and preferences.Methods/Design:PROFILe is a practice-based research comprising four
phases. The project focuses on patients with type 2 diabetes. During the first
study phase, patient profiles are drafted based on a systematic literature
research, latent class growth modeling, and expert collaboration. In phase 2,
the profiles are validated from a clinical, patient-related and statistical
perspective. Phase 3 involves a discrete choice experiment to gain insight into
the patient preferences that exist per profile. In phase 4, the results from all
analyses are integrated and recommendations formulated on which patient
characteristics should guide tailored chronic care.Discussion:PROFILe is an innovative study which uses a uniquely
holistic approach to assess the healthcare needs and preferences of chronically
ill. The patient profiles resulting from this project must be tested in practice
to investigate the effects of tailored management on patient experience,
population health and costs.