Polymicrobial Necrotizing Fasciitis in a Dog: The Involvement of Macrococcus caseolyticus, Proteus mirabilis, and Escherichia coli

Abstract

A male mixed breed dog was presented with two large wounds, extending the epidermis, dermis, and fascia: one at the dorsum of the thoracolumbar region and the other at the lumbosacral area. Lesions had extended inconspicuously to the dorsum of thorax affecting a large area, which showed regions with necrotic and crepitating foci after shaving. Based on histopathological and bacterial culture examinations, polymicrobial necrotizing fasciitis (NF) was diagnosed. Using the Bruker MALDI Biotyper identification technique, Macrococcus caseolyticus, Proteus mirabilis, and Escherichia coli were identified. Hitherto, there is no report on these bacteria linking them simultaneously to NF in a dog. In addition, the authors highlight other microbes associated with NF in humans and animals.

Characteristics of population structure, antimicrobial resistance, virulence factors, and morphology of methicillin-resistant Macrococcus caseolyticus in global clades

“…In China, Macrococcus caseolyticus has been isolated from many fermented foods, such as Chinese sausages and the specialty food "ChouGuiYu", a type of fermented mandarin fish [ 6 ]. Furthermore, M. caseolyticus can be isolated from human, animal, and raw meat during food processing and transportation [ 1 , 16 , 17 ], allowing it to be transmitted internationally via commercial shipments of agricultural products.…”

Genomic analysis of population structure, antimicrobial resistance, and virulent factors of methicillin-resistant Macrococcus caseolyticus in global lineages

“…Macrococcus caseolyticus is the foodborne bacterium detected in several fermented foods in China such as the Chinese sausages and the specialty food "ChouGuiYu", a type of fermented mandarin fish (Dai et al, 2013). Previous studies also described the colonization of M. caseolyticus on the surface of humans, animals, and raw meat during food processing and transportation (Acheampong et al, 2021;Jost et al, 2021;Keller et al, 2022), indicating that trade in agricultural products may lead to the bacterial transfer across countries.…”