Polymers with Amino Acids in Their Side Chain: Conformation of Polymers Derived from Glycylglycine and Phenylalanine

Methenitis, Constantinos; Morcellet, Joëlle; Pneumatikakis, G.; Morcellet, Michel

doi:10.1021/ma00084a027

Cited by 46 publications

(30 citation statements)

References 3 publications

(3 reference statements)

Supporting

Mentioning

Contrasting

Order By: Relevance

“…Thus, a thermodynamic study is of special interest, because it enables correlations to be established between increasing hydrophobicity and the appearance of a compact structure. 31,32 In the present study, we developed AgNPs in semi-IPN hydrogels composed of acrylamide and acryloyl phenylalanine in the presence of polyvinyl alcohol. The encased silver particles demonstrated very good antibacterial properties.…”

Section: 15mentioning

confidence: 99%

Fabrication of Amino Acid Based Silver Nanocomposite Hydrogels from PVA- Poly(Acrylamide-co-Acryloyl phenylalanine) and Their Antimicrobial Studies

Cha¹,

Babu²,

Rao³

et al. 2012

Bulletin of the Korean Chemical Society

View full text Add to dashboard Cite

New silver nanoparticle (AgNP)-loaded amino acid based hydrogels were synthesized successfully from poly (vinyl alcohol) (PVA) and poly(acryl amide-co-acryloyl phenyl alanine) (PAA) by redox polymerization. The formation of AgNP in hydrogels was confirmed by using a UV-Vis spectrophotometer and XRD. The structure and morphology of silver nanocomposite hydrogels were studied by using a scanning electron microscopy (SEM), which demonstrated scattered nanoparticles, ca. 10-20 nm. Thermogravimetric analysis revealed large differences of weight loss (i.e., 48%) between the prestine hydrogel and silver nanocomposite. The antibacterial studies of AgNP-loaded PAA (Ag-PAA) hydrogels was evaluated against Escherichia coli (Gram-negative) and Staphylococcus aureus (Gram-positive) bacteria. These Ag-PAA hydrogels showed significant activities against all the test bacteria. Newly developed hydrogels could be used for medical applications, such as artificial burn dressings.

show abstract

Section: 15mentioning

confidence: 99%

Fabrication of Amino Acid Based Silver Nanocomposite Hydrogels from PVA- Poly(Acrylamide-co-Acryloyl phenylalanine) and Their Antimicrobial Studies

Cha¹,

Babu²,

Rao³

et al. 2012

Bulletin of the Korean Chemical Society

View full text Add to dashboard Cite

show abstract

“…Amino acids have been used as chiral substituents in polymers since the late 1960s, with the pioneering studies of Iwakura et al [67,68] Later many amino acids were used, such as L-alanine (extensively studied by Morcellet and coworkers), [69][70][71][72][73][74][75][76] L-phenyl alanine and L-glycine, [77] Lleucine [78][79][80][81] and others (for a review see ref. [82]).…”

Section: Optical Activity and Circular Dichroism Measurementsmentioning

confidence: 99%

Thiol‐Ene Radical Addition of L‐Cysteine Derivatives to Low Molecular Weight Polybutadiene

Lotti

Coiai

Ciardelli

et al. 2009

Macro Chemistry & Physics

View full text Add to dashboard Cite

The functionalisation of a low molecular weight, liquid 1,2‐polybutadiene (PBL) was performed by the addition of either N‐acetyl‐L‐cysteine or its methyl ester through the thiol‐ene radical reaction. The functionalisation runs were carried out in 1,4‐dioxane solution and in the presence of a free radical initiator (2,2′‐azobisisobutyrronitrile, AIBN). The initial feed ratio polymer/cysteine derivative/initiator was varied, in order to highlight the occurrence of side reactions and to understand their possible influence on the process. The 1H NMR determination of the functionalisation degree brought out high addition degrees of thiols, regardless of the initial thiol/double bonds ratio. This caused a drastic change in the macroscopic properties of the PBL with improved solubility in hydrophilic solvents (for instance in alkaline aqueous solutions) and impressive increase of the glass transition temperature. The propagation of chiral properties from the functionalising agents to the modified polymers was evaluated by polarimetry and circular dichroism in solution.magnified image

show abstract

“…6'7 Thus, it was shown that poly(methacrylamides) bearing glycine residues in their side chains behave as normal weak polyelectrolytes, while poly( methacrylamides) bearing phenylalanine residues adopt a compact conformation at low pH, stabilized by the hydrophobic attraction of the phenyl groups. 8 Casolaro and coworkers have reported the preparation of copolymers of N-isopropylacrylamide (NIPAM) and acrylamides or methacrylamides containing L-valine or L-leucine residues . 9 • 10 • 11 Other copolymers of acrylamides bearing amino acid residues and Nalkylacrylamides have been described, 12 • 13 • 14 but copolymers of NIP AM are unique, since the properties of their aqueous solutions depend not only on pH, but also on temperature.…”

mentioning

confidence: 99%

Solution Properties of Hydrophobically-Modified Copolymers of N-Isopropylacrylamide and N-L-Valine Acrylamide. A Study by Fluorescence Spectroscopy and Microcalorimetry

Poncet-Legrand

Winnik

2001

Polym J

View full text Add to dashboard Cite

Polymers with Amino Acids in Their Side Chain: Conformation of Polymers Derived from Glycylglycine and Phenylalanine

Cited by 46 publications

References 3 publications

Fabrication of Amino Acid Based Silver Nanocomposite Hydrogels from PVA- Poly(Acrylamide-co-Acryloyl phenylalanine) and Their Antimicrobial Studies

Fabrication of Amino Acid Based Silver Nanocomposite Hydrogels from PVA- Poly(Acrylamide-co-Acryloyl phenylalanine) and Their Antimicrobial Studies

Thiol‐Ene Radical Addition of L‐Cysteine Derivatives to Low Molecular Weight Polybutadiene

Solution Properties of Hydrophobically-Modified Copolymers of N-Isopropylacrylamide and N-L-Valine Acrylamide. A Study by Fluorescence Spectroscopy and Microcalorimetry

Contact Info

Product

Resources

About