Polymerization of PEDOT/PSS/Chitosan-Coated Electrodes for Electrochemical Bio-Sensing

Abstract

Poly(3,4-ethylenedioxythiophene) (PEDOT) doped with poly (styrene sulfonate) (PSS) has a variety of chemical and biomedical applications. Additionally, chitosan has been extensively used in industrial and medical fields. However, whether chitosan could be incorporated into conducting polymers of PEDOT/PSS is not clear. In this study, the PEDOT/PSS/chitosan coatings were electrochemically polymerized on the surface of 0.5 mm platinum (Pt) electrodes and the properties of electrochemical cyclic voltammetry (CV) and electrochemical impedance spectroscopy (EIS) of the PEDOT/PSS/chitosan-coated electrodes were investigated. Furthermore, PEDOT/PSS/chitosan-coated electrodes used for electrochemical bio-sensing, using dexamethasone (Dex) as a model bio-sensing material, were examined.The results demonstrated that PEDOT/PSS/chitosan-coated electrodes were stable in phosphate-buffered saline (PBS) solution. The electrochemical CV curve areas, reflecting the charge delivery capacity, and the EIS of the PEDOT/PSS/chitosan-coated electrodes were sensitive to Dex, and the good linearity can be obtained between CV curve areas, the EIS and the concentration of Dex. In addition, electrochemical sensitivity of the PEDOT/PSS/chitosan-coated electrodes to Dex was much higher than ultraviolet (UV) spectroscopy detection. All these results revealed that the PEDOT/PSS/chitosan-coated electrodes can be electrochemical polymerized and used for electrochemical bio-sensing.

A Novel Highly Sensitive Electrochemical Nitrite Sensor Based on a AuNPs/CS/Ti3C2 Nanocomposite

“…Researchers found that MXene nanosheets could be potential supporting materials due to the large surface area, and other nanomaterials used in the decoration of MXene sheets can effectively solve the interlayer aggregation and application in electrochemical sensors [ 23 , 24 ]. Chitosan (CS) is one of the natural amino polysaccharides which have an excellent film-forming ability, and are cost effective, environmentally friendly, and biocompatible [ 25 , 26 ]. Although CS cannot conduct electricity, it is often used in electrochemical sensors because of its excellent property of biocompatibility and film-forming ability.…”

In Situ Reduction of Silver Nanoparticles on the Plasma-Induced Chitosan Grafted Polylactic Acid Nonwoven Fabrics for Improvement of Antibacterial Activity

“…Polylactic acid (PLA) has been regarded as the most promising sustainable and biodegradable fiber to replace conventional polyethylene terephthalate (PET) polyester fiber in textile products. It is also widely used in medical and health, agriculture and forestry protection, and packaging materials due to its good physical and mechanical properties, excellent biocompatibility, and natural degradation [1][2][3]. However, there are still some disadvantages in the properties of PLA materials, such as high inertia, poor hydrophilicity and difficulty to react with other substances, which greatly limit the further development of PLA in the field of biomedical functional materials [4,5].…”

PEDOT Thin Films with n-Type Thermopower

“…Doping mechanisms involve reduction states that are not stable in air. − Therefore, there is currently major scientific interest in the search for a stable n-type conducting polymer for the manufacture of thermoelectric modules . Intrinsically conducting polymers (ICPs) are attracting widespread attention due to their promise in organic light-emitting diodes (OLEDs), , organic solar cells (OSC), , supercapacitors, − and thermoelectric devices. , They exhibit several desirable properties, including flexibility, low cost, ease of chemical modification, and flexible processing, which render them a viable alternative to inorganic semiconductors. − Thin ICP films are being used as coatings also for corrosion protection as well as electromagnetic shields, radar absorbers, sensors, , and polymeric actuators . There has been an ever increasing number of scientific studies dedicated to these topics in recent years …”

“…The maximum thermoelectric efficiency is obtained when doping levels are optimized to produce the maximum power factor (= S 2 σ) and the minimum thermal conductivity. Generally, electrical conductivity increases when the Seebeck coefficient decreases, ,, , while it is known that nanostructuration of a material improves the Seebeck coefficient by phonon scattering which reduces thermal conductivity. ,, …”

“…12,13 They exhibit several desirable properties, including flexibility, low cost, ease of chemical modification, and flexible processing, which render them a viable alternative to inorganic semiconductors. 14−16 Thin ICP films are being used as coatings also for corrosion protection 17 as well as electromagnetic shields, 18 radar absorbers, 19 sensors, 20,21 and polymeric actuators. 22 There has been an ever increasing number of scientific studies dedicated to these topics in recent years.…”