1984
DOI: 10.1159/000233427
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Polymerization of Individual Species of Tree Pollen Allergens

Abstract: This report describes the preparation of individual tree pollen allergen polymers in contrast to our previous description of the polymerization of a mixture of tree pollens. These individual polymers may be used for immunotherapy as indicated by the IgE-mediated reactivity of each patient. A modified chromatographic fractionation process was used which results in tree polymers with skin reactivity 1,000- to 10,000-fold less from monomers and with a defined lower molecular weight limit. The modified preparative… Show more

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Cited by 6 publications
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“…Chemically modified allergens have been shown useful in hyposensitiza tion therapy [2,16,[26][27][28]31]. Unlike the native mole cules, they are used for hyposensitization treatment with less risks of unwarranted effects [20,21,25].…”
Section: Introductionmentioning
confidence: 99%
“…Chemically modified allergens have been shown useful in hyposensitiza tion therapy [2,16,[26][27][28]31]. Unlike the native mole cules, they are used for hyposensitization treatment with less risks of unwarranted effects [20,21,25].…”
Section: Introductionmentioning
confidence: 99%