Polymerization of Chitosan-Acrylic Salt for Use in Dentistry

Qu, Xin; Wrzyszczyński, Andrzej; Pielichowski, Krzysztof; Pielichowski, Jan; Adamczak, E.; Morge, S.; Lindén, Lars‐Åke; Rabek, Jan F.

doi:10.1080/10601329708014338

Cited by 11 publications

(5 citation statements)

References 25 publications

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“…There is currently a considerable interest in the preparation of controlled release systems and other biomedical applications. [1,[11][12][13] In previous publications, [14,15] we reported the preparation and characterization of chitosan/polyacrylic acid networks by the free radical polymerization of acrylic acid Full Paper: Porous microspheres have been prepared by suspension free radical polymerization of acrylic acid (AA) in the presence of chitosan (CHI). The microspheres were characterized by FTIR and environmental SEM.…”

Section: Introductionmentioning

confidence: 99%

Drug Delivery Systems Based on Porous Chitosan/Polyacrylic acid Microspheres

Péniche

Fernández

Gallardo

et al. 2003

Macromolecular Bioscience

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Porous microspheres have been prepared by suspension free radical polymerization of acrylic acid (AA) in the presence of chitosan (CHI). The microspheres were characterized by FTIR and environmental SEM. The PAA content of the microspheres was estimated to be in the range 45–50 wt.‐%. The swelling degree of these particles is almost constant in the range 2 < pH < 5, but it increases considerably as the pH is raised from 5 to 10. The release profiles of microspheres loaded with meclofenamic acid (MF) were determined at pH 2, 7.4, and 10. The in vitro release of MF at different pHs was modulated by the solubility of the drug. These microcapsules are biodegradable and presented good biocompatibility and biodegradability during in vivo experiments.ESEM microphotograph of the porous PAA/CHI microspheres.magnified imageESEM microphotograph of the porous PAA/CHI microspheres.

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Section: Introductionmentioning

confidence: 99%

Drug Delivery Systems Based on Porous Chitosan/Polyacrylic acid Microspheres

Péniche

Fernández

Gallardo

et al. 2003

Macromolecular Bioscience

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“…The evolution of water is associated with the polymer at temperatures below 180°C. The degradation step at 250°C is interpreted as the result of intermolecular or intramolecular dehydration followed by decarboxylation 14, 15. The last degradation step starts beyond 350°C, at which temperature the bulk decomposition of the polymer takes place, giving rise to a highly unsaturated structure 14.…”

Section: Resultsmentioning

confidence: 99%

Radiation synthesis and characterization of poly(N‐vinyl‐2‐pyrrolidone/acrylic acid) and poly(N‐vinyl‐2‐pyrrolidone/acrylamide) hydrogels for some metal‐ion separation

Hegazy

El‐Aal

Taleb

et al. 2004

J of Applied Polymer Sci

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Two different hydrogels, prepared from N-vinyl-2-pyrrolidone/acrylic acid (NVP/AAc) and N-vinyl-2-pyrrolidone/acrylamide (NVP/AAm), were studied for the separation and extraction of some heavy-metal ions from wastewater. The hydrogels were prepared by the ␥-radiation-induced copolymerization of the aforementioned binary monomer mixtures. Further modification was carried out for the NVP/AAc copolymer through an alkaline treatment to improve the swelling behavior by the conversion of the carboxylic acid groups into its sodium salts. The thermal stability and swelling properties were also investigated as functions of the N-vinyl-2-pyrrolidone content. The characterization and some selected properties of the prepared hydrogels were studied, and the possibility of their practical use in wastewater treatment for heavy metals such as Cu, Ni, Co, and Cr was investigated. The maximum uptake for a given metal was higher for a treated NVP/AAc hydrogel than for an untreated NVP/AAc hydrogel and was higher for an untreated NVP/AAc hydrogel than for an NVP/ AAm hydrogel.

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“…In the field of endodontics, antimicrobial root canal materials including types of sealers, pastes, and cement were tested to evaluate their efficacy. 35 Intrinsically antimicrobial hydrogels were developed for periodontal reconstruction 36 and for blocking the microchannels of dentin, 37 even though no information concerning their injectability was reported. Just before entering the next decade, superporous hydrogels started to be studied as drug delivery platforms.…”

Section: Reviewmentioning

confidence: 99%