Polymeric Imidazoles and Imidazoliums in Nanomedicine: Comparison to Ammoniums and Phosphoniums

Allen, Michael; Hemp, Sean T.; Long, Timothy Edward

doi:10.1007/978-3-662-44903-5_9

Cited by 2 publications

(2 citation statements)

References 189 publications

Supporting

Mentioning

Contrasting

Order By: Relevance

“…Table 1 highlights a variety of reviews focusing on applications of PILs in energy materials, devices, and biomedical materials. 29,33,38,[43][44][45]56,59,62 The types of the applications we discuss here are summarized in Figure 28.…”

Section: Applicationsmentioning

confidence: 99%

Polymerized and Colloidal Ionic Liquids─Syntheses and Applications

Li,

Yan,

Texter

2024

Chem. Rev.

View full text Add to dashboard Cite

The breadth and importance of polymerized ionic liquids (PILs) are steadily expanding, and this review updates advances and trends in syntheses, properties, and applications over the past five to six years. We begin with an historical overview of the genesis and growth of the PIL field as a subset of materials science. The genesis of ionic liquids (ILs) over nano to meso lengthscales exhibiting 0D, 1D, 2D, and 3D topologies defines colloidal ionic liquids, CILs, which compose a subclass of PILs and provide a synthetic bridge between IL monomers (ILMs) and micro to macroscale PIL materials. The second focus of this review addresses design and syntheses of ILMs and their polymerization reactions to yield PILs and PIL-based materials. A burgeoning diversity of ILMs reflects increasing use of nonimidazolium nuclei and an expanding use of step-growth chemistries in synthesizing PIL materials. Radical chain polymerization remains a primary method of making PILs and reflects an increasing use of controlled polymerization methods.Step-growth chemistries used in creating some CILs utilize extensive cross-linking. This cross-linking is enabled by incorporating reactive functionalities in CILs and PILs, and some of these CILs and PILs may be viewed as exotic cross-linking agents. The third part of this update focuses upon some advances in key properties, including molecular weight, thermal properties, rheology, ion transport, self-healing, and stimuli-responsiveness. Glass transitions, critical solution temperatures, and liquidity are key thermal properties that tie to PIL rheology and viscoelasticity. These properties in turn modulate mechanical properties and ion transport, which are foundational in increasing applications of PILs. Cross-linking in gelation and ionogels and reversible step-growth chemistries are essential for self-healing PILs. Stimuli-responsiveness distinguishes PILs from many other classes of polymers, and it emphasizes the importance of segmentally controlling and tuning solvation in CILs and PILs. The fourth part of this review addresses development of applications, and the diverse scope of such applications supports the increasing importance of PILs in materials science. Adhesion applications are supported by ionogel properties, especially crosslinking and solvation tunable interactions with adjacent phases. Antimicrobial and antifouling applications are consequences of the cationic nature of PILs. Similarly, emulsion and dispersion applications rely on tunable solvation of functional groups and on how such groups interact with continuous phases and substrates. Catalysis is another significant application, and this is an historical tie between ILs and PILs. This component also provides a connection to diverse and porous carbon phases templated by PILs that are catalysts or serve as supports for catalysts. Devices, including sensors and actuators, also rely on solvation tuning and stimuliresponsiveness that include photo and electrochemical stimuli. We conclude our view of applications with 3D printi...

show abstract

Section: Applicationsmentioning

confidence: 99%

Polymerized and Colloidal Ionic Liquids─Syntheses and Applications

Li,

Yan,

Texter

2024

Chem. Rev.

View full text Add to dashboard Cite

show abstract

“…Material extrusion generally does not result in potentially harmful byproducts, which plagues other methods of AM . As a result of the decreased toxicity concern, extrudable water-soluble and biodegradable polymers act as small molecule delivery agents for biological applications. − These polymers, found in nature and synthetic chemistry, include poly(ethylene glycol) (PEG), poly(lactide- co -glycolide), and poly(vinyl alcohol) (PVOH). , A number of water-soluble polymers enable delivery of genes or water-insoluble drugs, which have previously exhibited low bioavailability to the human body. ,, Few examples exist of water-soluble polymers which have suitable rheological and mechanical properties necessary for AM via material extrusion . Commercially, PVOH offers sufficient rheological properties to act as a water-soluble filament for material extrusion at high temperatures, necessitating the development of additional materials for low-temperature printing of water-soluble material extrusion parts .…”

Section: Introductionmentioning

confidence: 99%

Poly(ether ester) Ionomers as Water-Soluble Polymers for Material Extrusion Additive Manufacturing Processes

Pekkanen

Zawaski

Stevenson

et al. 2017

ACS Appl. Mater. Interfaces

Self Cite

View full text Add to dashboard Cite

Water-soluble polymers as sacrificial supports for additive manufacturing (AM) facilitate complex features in printed objects. Few water-soluble polymers beyond poly(vinyl alcohol) enable material extrusion AM. In this work, charged poly(ether ester)s with tailored rheological and mechanical properties serve as novel materials for extrusion-based AM at low temperatures. Melt transesterification of poly(ethylene glycol) (PEG, 8k) and dimethyl 5-sulfoisophthalate afforded poly(ether ester)s of sufficient molecular weight to impart mechanical integrity. Quantitative ion exchange provided a library of poly(ether ester)s with varying counterions, including both monovalent and divalent cations. Dynamic mechanical and tensile analysis revealed an insignificant difference in mechanical properties for these polymers below the melting temperature, suggesting an insignificant change in final part properties. Rheological analysis, however, revealed the advantageous effect of divalent countercations (Ca, Mg, and Zn) in the melt state and exhibited an increase in viscosity of two orders of magnitude. Furthermore, time-temperature superposition identified an elevation in modulus, melt viscosity, and flow activation energy, suggesting intramolecular interactions between polymer chains and a higher apparent molecular weight. In particular, extrusion of poly(PEG-co-CaSIP) revealed vast opportunities for extrusion AM of well-defined parts. The unique melt rheological properties highlighted these poly(ether ester) ionomers as ideal candidates for low-temperature material extrusion additive manufacturing of water-soluble parts.

show abstract

Polymeric Imidazoles and Imidazoliums in Nanomedicine: Comparison to Ammoniums and Phosphoniums

Cited by 2 publications

References 189 publications

Polymerized and Colloidal Ionic Liquids─Syntheses and Applications

Polymerized and Colloidal Ionic Liquids─Syntheses and Applications

Poly(ether ester) Ionomers as Water-Soluble Polymers for Material Extrusion Additive Manufacturing Processes

Contact Info

Product

Resources

About