Polymerase Chain Reaction in the Diagnosis of Invasive Aspergillosis in Hematopoietic Stem Cell Transplant Recipients: A Meta-Analysis of Diagnostic Performance
Abstract:Background: Invasive aspergillosis (IA) is associated with significant morbidity and mortality among hematopoietic-stem cell transplant (HSCT) recipients. Timely and accurate diagnosis of an active infection is needed in order to initiate targeted antifungal therapy. Although previous studies have assessed the performance of Aspergillusspp. PCR with promising findings, PCR has not yet been incorporated in the diagnostic algorithms by the guideline issuing organizations.
Aim: Our goal was to eval… Show more
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