Polymer Iodination for Improved in Vitro Tracking of Biodegradable Stent Degradation: Serial Microct Imaging for Bioreactor Testing

Winters, James; Lee, Jung Seok; Guelcher, Manfred; Mathur, Anthony; Martin, John F.; Fahmy, Tarek M.; Sinusas, Albert J.

doi:10.1016/s0735-1097(14)61049-4

Cited by 1 publication

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“…ECs or EPCs are usually added into the incubating loop to test the cell capturing efficiency of the tested stent. Stent bioreactors resemble the design of VTE bioreactors, with the outer medium-replenishing loop absent and with a roller pump instead of a pulsatile one [51]. Weinandy et al used a stent bioreactor system to test the endothelialization of BioStent (a nitinol stent covered with fibrin gel) with ECs added into the loop resulting is successful cell anchoring, growth and generation of ECMs in-situ ( Figure 3) [52].…”

Section: Bioreactors For Stentsmentioning

confidence: 99%

Bioreactors for tissue engineering: An update

Zhao

Griffin

Cai

et al. 2016

Biochemical Engineering Journal

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One of the greatest puzzles in wound healing is how to substitute or replace the defect caused by loss and damaged tissue or organs. In regenerative medicine, Tissue Engineering has been proposed to supply this demand by generating tissues in vitro. Bioreactors are the key to translate these cells and tissue-based constructs into large-scale biological products that are clinically effective, safe and financially pliable. In this review, we summarise the different upto-date bioreactor designs being used for different cell types and special design scaffolds, and highlight advantages of different bioreactors, current challenges and the future trends. It is our belief that with efforts combined from multiple disciplinary participants, a novel bioreactor system that is capable of fast, large scale tissue culture would come about in near future.

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Section: Bioreactors For Stentsmentioning

confidence: 99%