Polymer brush nanopatterns with controllable features for protein pattern applications

Li, Yunfeng; Zhang, Junhu; Fang, Liping; Jiang, Li; Liu, Wendong; Wang, Tieqiang; Sun, Hongchen; Yang, Bai

doi:10.1039/c2jm35197h

Cited by 32 publications

(35 citation statements)

References 59 publications

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“…[1] Microscale surface patterning with polymer brushes has recently attracted increasing attention owing to potential applications in areas such as biosensors, [2] biocompatible materials, [3] and protein immobilization. [4] Surfaces can be functionalized in as patially controlled fashion by applying photo-induced reactions.I nr ecent years,light-induced modular ligation reactions [5] that provide spatial control over the surface grafting and light-controlled/ living radical polymerization techniques have been developed. [6] Several photo-induced reactions,i ncluding Diels-Alder, [7,8] thiol-ene, [9] thiol-quinone, [10] and thiol-yne [11] ligations,h ave been applied to attach functional groups and biomolecules to surfaces and to control patterning.…”

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confidence: 99%

Macromolecular Surface Design: Photopatterning of Functional Stable Nitrile Oxides

et al. 2015

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The efficient trapping of photogenerated thioaldehydes with functional shelf-stable nitrile oxides in a 1,3-dipolar cycloaddition is a novel and versatile photochemical strategy for polymer end-group functionalization and surface modification under mild and equimolar conditions. The modular ligation in solution was followed in detail by electrospray ionization mass spectrometry (ESI-MS). X-ray photoelectron spectroscopy (XPS) was employed to analyze the functionalized surfaces, whereas time-of-flight secondary-ion mass spectrometry (ToF-SIMS) confirmed the spatial control of the surface functionalization using a micropatterned shadow mask. Polymer brushes were grown from the surface in a spatially confined regime by surface-initiated atom transfer radical polymerization (SI-ATRP) as confirmed by TOF-SIMS, XPS as well as ellipsometry.

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confidence: 99%

Macromolecular Surface Design: Photopatterning of Functional Stable Nitrile Oxides

et al. 2015

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“…Diverse arrays have generated by integrating multiple colloidal lithography methods . Yang and co‐workers utilized silica or polystyrene (PS) colloidal crystals as masks and took full advantage of reactive ion etching (RIE) to fabricate a series of ordered cone, pillar, hole, well, and elliptical ring arrays . The same group combined the RIE and CVD to attain a microstructure of gold/PS Janus‐spheres.…”

Section: Tailoring Ordered Photonic Micro/nanostructurementioning

confidence: 99%

Section: Tailoring Ordered Photonic Micro/nanostructurementioning

confidence: 99%

“…Finally, SI‐ATRP allowed the preparation of elliptical ring PHEMA brush and the modification of protein (Figure B). [79d] As the extension of what, many multiscale patterns of proteins can be attained with the PHEMA brush as templates. In Figure C, the fluorescent photographs of multiscale IgG patterns (microdisc, microring, microtriangle, and microgrid) after covalently bonding FITC‐anti‐IgG are exhibited.…”

Section: Tailoring Ordered Photonic Micro/nanostructurementioning

confidence: 99%

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Ordered Hybrid Micro/Nanostructures and Their Optical Applications

Zhang

Yang

2019

Advanced Optical Materials

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known that the optical properties related refractive index is an important parameter for ordered micro/nanostructures. Commonly, organic substances own lower refraction. Aiming at improving which, researchers introduce highly polarizable heteroatoms or rigid aromatic moieties. However, the maximum of refractive index is limited to 1.54-1.60, [3] which is far from the requirements of rapidly developing technologies. [4] Incorporation of inorganic materials with relative higher refractive index (TiO 2 , ZnO, ZnS, graphene nanoparticles, and Si) into an organic matrix is capable of enlarging the optical parameters to a great extent, generally up to a value of 2.5-3.0, [5] which offers more chances for the fabrication of novel ordered micro/nanostructures. Photonic crystals (PCs), for example, regularly arrange materials of high and low dielectric constants on the order of the wavelength of light. The photonic bandgap (PBG) prohibiting the propagation of light results from the sufficient dielectric contrast and appropriate geometry. The structural color therefore generates. Manipulating the propagation of light via micro/nanostructures meets the requirements for modern optical devices. [6] As a result, more efforts have been applied to devices consisting of micro/nanostructures of multiple materials, such as synthetic materials and biomaterials. [7] Besides optical properties, the strength and toughness of ordered micro/nanostructures are also improved based on the hybrid material. Meanwhile, the electric and magnetic features of inorganic dopants can also exactly assist the adjustability. Therefore, the hybrid can significantly improve performance compared with its constituent.This review emphasizes on applications sought (sensing, imaging, communication, photoelectricity, etc.), the materials used (silicon, metals, polymers, etc.), and the preparation methods employed (patterning, etching, deposition, etc.). We present an attempt to classify and compare some intensively reported micro/nanostructures of hybrid materials and/or heterogeneous structures, along with recent important developments in literatures. It is organized as follows: First, we summarize some fundamental physical principles and concepts in brief. Second, we particularly highlight artificial and natural laminar structures, represented by Bragg stacks (BSs) and butterfly wings, which have drawn much attention in the latest literatures. Next, the focus shifts to the preparation routes and materials adoption of colloidal crystals and their derived periodic arrays. A few examples of highly functional materials Recent advances in manufacturing and technology of ordered hybrid micro/ nanostructures have acquired many breakthroughs. With the aid of the cooperation of various materials, the ordered hybrid micro/nanostructures exhibit high-quality performance and mechanical stability and allow the modulation on the light-matter interaction in a controllable manner, thereby enabling a wide variety of innovative applications. This article reviews recent deve...

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“…Die kontrollierte Immobilisierung von Biomolekülen, wie Peptiden und Proteinen, in einem bestimmten Bereich und Ausmaß auf der Oberfläche eines festen Substrats ist in der Biotechnologie von fundamentaler Bedeutung. [1] Die mikroskalige Oberflächenmusterung mit Polymerbürsten findet wegen mçglicher Anwendungen in Gebieten wie Biosenso-ren, [2] biokompatiblen Materialien [3] und Proteinimmobilisierung [4] zunehmende Aufmerksamkeit. Oberflächen kçnnen durch Anwendung photoinduzierter Reaktionen räumlich kontrolliert funktionalisiert werden.…”

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Makromolekulare Oberflächen: Photomusterung mit funktionellen stabilen Nitriloxiden

et al. 2015

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Das effiziente Abfangen photogenerierter Thioaldehyde durch funktionelle stabile Nitriloxidei ne iner 1,3-dipolaren Cycloaddition ist eine neue und vielseitige photochemische Strategie zur Funktionalisierung von Polymeren und zur Oberflächenmodifikation unter milden und äquimolaren Bedingungen. Die modulare Ligation in Lçsung wird im Detail durchE SI-MS verfolgt. XPS wird zur Analyse der funktionalisierten Oberflächen verwendet, während ToF-SIMS die durch Anwendung einer Schattenmaske erreichte räumli-cheK ontrolle der Oberflächenfunktionalisierung belegt. Polymerbürsten wurden in einem räumlich begrenzten Bereich durch SI-ATRP von der Oberfläche aus wachsen gelassen, was mithilfe von ToF-SIMS,XPS sowie Ellipsometrie belegt wird. Die kontrollierte Immobilisierung von Biomolekülen, wie Peptiden und Proteinen, in einem bestimmten Bereich und Ausmaß auf der Oberfläche eines festen Substrats ist in der Biotechnologie von fundamentaler Bedeutung. [1] Die mikroskalige Oberflächenmusterung mit Polymerbürsten findet wegen mçglicher Anwendungen in Gebieten wie Biosenso-ren, [2] biokompatiblen Materialien [3] und Proteinimmobilisierung [4] zunehmende Aufmerksamkeit. Oberflächen kçnnen durch Anwendung photoinduzierter Reaktionen räumlich kontrolliert funktionalisiert werden. In jüngster Zeit wurden photoinduzierte modulare Ligationsreaktionen, [5] die eine räumliche Kontrolle der Oberflächenpfropfung ermçglichen, und lichtkontrollierte/lebende radikalische Polymerisationen entwickelt. [6] Einige photoinduzierte Reaktionen, darunter Diels-Alder-, [7,8] Thiol-En-, [9] Thiol-Chinon- [10] und Thiol-Alkin-Ligationen, [11] wurden zur Verankerung von funktionellen Gruppen und Biomolekülen auf Oberflächen und zur Kontrolle der Musterung angewendet. So wurde jüngst von uns und anderen über photogenerierte Cyclooctine, [12] Nitrilimine, [13] Oxime [14] und o-Naphthochinonmethide, [15] die effizient durch Dienophile abgefangen werden kçnnen, berichtet. Des Weiteren haben wir 2013 das Abfangen photogenerierter Thioaldehyde in einer Diels-Alder-Reaktion als effiziente Methode für räumlich kontrolliertes Oberflächendesign eingeführt. [16] Die Photofragmentierung von Phenacylsulfiden (d. h. photoaktivierbaren Thioaldehyden) ist eine milde und effiziente Methode zur Herstellung hochreaktiver Thioaldehyde,die in situ durch Diene,Nucleophile [17] oder in einer 1,3-dipolaren Cycloaddition mit Nitronatestern [18,19] abgefangen werden kçnnen.Nitriloxide gehçren zu den reaktivsten Spezies in der organischen Chemie und werden gewçhnlich durch 1,3-dipolare Cycloaddition abgefangen. [20,21] Die Cycloaddition zwischen Nitriloxiden und Alkinen ist eine metallfreie Ligationsreaktion, die für die Modifikation von Polymerendgruppenv erwendet wurde. [22] Allerdings werden die Nitriloxide wegen ihrer schnellen Dimerisierung zu Furoxanen in situ aus Oximvorstufen hergestellt, wodurch die Anwendbarkeit in modularen Ligationsstrategien stark eingeschränkt wird. Spontane Dimerisierung zu Furoxanen kann durch Substituenten am aromatischen Ring, an dem sich die...

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Polymer brush nanopatterns with controllable features for protein pattern applications

Cited by 32 publications

References 59 publications

Macromolecular Surface Design: Photopatterning of Functional Stable Nitrile Oxides

Macromolecular Surface Design: Photopatterning of Functional Stable Nitrile Oxides

Ordered Hybrid Micro/Nanostructures and Their Optical Applications

Makromolekulare Oberflächen: Photomusterung mit funktionellen stabilen Nitriloxiden

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