Polyhedral vesicles with crystalline bilayers formed from catanionic surfactant mixtures of fluorocarbon and hydrocarbon amphiphiles

Zhang, Juan; Xu, Guiying; Zhou, Yong‐Gui; Zhou, Ting; Zhai, Xueru

doi:10.1016/j.jcis.2013.06.025

Cited by 17 publications

(12 citation statements)

References 44 publications

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“…Zhang et al . determined the interlamellar spacing of the multilamellar polyhedral vesicles formed by perfluorononanoic acid (C8F17COOH) and tetradecyltrimethylammonium hydroxide (TTAOH) mixtures in aqueous solution by SAXS56. Dias et al .…”

Section: Resultsmentioning

confidence: 99%

A Light-Responsive Self-Assembly Formed by a Cationic Azobenzene Derivative and SDS as a Drug Delivery System

Geng

Wang

et al. 2017

Sci Rep

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The structure of a self-assembly formed from a cationic azobenzene derivative, 4-cholesterocarbonyl-4′-(N,N,N-triethylamine butyloxyl bromide) azobenzene (CAB) and surfactant sodium dodecyl sulfate (SDS) in aqueous solution was studied by cryo-TEM and synchrotron radiation small-angle X-ray scattering (SAXS). Both unilamellar and multilamellar vesicles could be observed. CAB in vesicles were capable to undergo reversible trans-to-cis isomerization upon UV or visible light irradiation. The structural change upon UV light irradiation could be catched by SAXS, which demonstrated that the interlamellar spacing of the cis-multilamellar vesicles increased by 0.2–0.3 nm. Based on this microstructural change, the release of rhodamine B (RhB) and doxorubicin (DOX) could be triggered by UV irradiation. When incubated NIH 3T3 cells and Bel 7402 cells with DOX-loaded CAB/SDS vesicles, UV irradiation induced DOX release decreased the viability of both cell lines significantly compared with the non-irradiated cells. The in vitro experiment indicated that CAB/SDS vesicles had high efficiency to deliver loaded molecules into cells. The in vivo experiment showed that CAB/SDS vesicles not only have high drug delivery efficiency into rat retinas, but also could maintain high drug concentration for a longer time. CAB/SDS catanionic vesicles may find potential applications as a smart drug delivery system for controlled release by light.

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Section: Resultsmentioning

confidence: 99%

A Light-Responsive Self-Assembly Formed by a Cationic Azobenzene Derivative and SDS as a Drug Delivery System

Geng

Wang

et al. 2017

Sci Rep

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“…Such polyhedral structure formation in MCVs can be due to the balance of synergistic and hydrophobic interactions between oppositely charged surfactants. Usually, the polyhedral structure of catanionic vesicles is achieved by employing a heating and cooling effect to the mixture, but in our case, we can get these structures without heating. − …”

Section: Resultsmentioning

confidence: 95%

Efficient Photodynamic Therapy against Gram-Positive and Gram-Negative Bacteria Using Rose Bengal Encapsulated in Metallocatanionic Vesicles in the Presence of Visible Light

Sharma

Thakur

Kaur

et al. 2020

ACS Appl. Bio Mater.

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Significant consumption of antibiotics has generated multidrug resistance in bacteria, which is a major menace to human beings. Antibacterial photodynamic therapy (aPDT) is a progressing technique for inhibition of bacterial infection with minimal side effects. Metals and delivering agents play a major role in aPDT efficiency. Herein, we report a formulation to enrich the antibacterial photodynamic therapy utilizing metallocatanionic vesicles (MCVs) against both Gram-positive and Gram-negative bacteria. These MCVs were synthesized by utilizing iron-based double-chain metallosurfactant [FeCPC(II)] as a cationic surfactant and AOT, a double-chain anionic surfactant. These synthesized MCV fractions were characterized by distinct techniques like DLS, zeta potential, FE-SEM, confocal microscopy, SAXS, and UV–Visible spectroscopy. Polyhedral-shaped MCVs with a size of 200 nm were formed, wherein the charge and size of the catanionic vesicle can be controlled by varying the mixing ratios. Both Gram-positive bacteria, i.e., methicillin-resistant Staphylococcus aureus (MRSA), and Gram-negative bacteria, i.e., Escherichia coli (E. coli), were used for aPDT using Rose Bengal (RB) as a photosensitizer (PS) encapsulated in MCVs in the presence of a 532 nm wavelength laser. The aPDT against bacterial cells was evaluated for both dark and light toxicities. Pure MCVs also exhibited good antibacterial properties; however, much enhancement was observed in the presence of RB encapsulated in MCVs under light, where eradication of bacteria (E. coli and MRSA) was achieved in 30 min. The observations demonstrated that it is the presence of metal that enhances the singlet oxygen quantum yield of RB and MCVs help in retarding self-quenching and enhanced solubilization of RB. The cationic surfactant-rich fraction shows strong adhesion toward bacteria via electrostatic interactions. The outcome of this research shows that these newly fabricated metal-based metallocatanionic vesicles were effective against both Gram-positive and Gram-negative bacteria using aPDT and must be exploited for clinical applications as well as an alternative for antibiotics in the future.

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“…[12][13][14][15][16][17][18][19][20][21][22] Until now, non-spherical fatty acid vesicles, especially polyhedral ones, have been rarely reported. 24 Nowadays, fluorinated colloids have been used in blood substitute, drug delivery and other potential biomedical applications. 23 Uniquely, when anionic fluorosurfactants were mixed with cationic hydrocarbon surfactants, polyhedral vesicles were formed in such catanionic surfactant mixtures.…”

Section: Introductionmentioning

confidence: 99%

“…23 Uniquely, when anionic fluorosurfactants were mixed with cationic hydrocarbon surfactants, polyhedral vesicles were formed in such catanionic surfactant mixtures. 24 Nowadays, fluorinated colloids have been used in blood substitute, drug delivery and other potential biomedical applications. 25,26 It is well known that compared with hydrogenated carboxylic acids, fluorosurfactants own unique physicochemical properties because of the fluorocarbon chains such as high surface activity, hydrophobic and oleophobic properties, and chemical stability.…”

Section: Introductionmentioning

confidence: 99%

Faceted fatty acid vesicles formed from single-tailed perfluorinated surfactants

Zhang

Song

et al. 2015

Soft Matter

Self Cite

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The aggregation behavior and rheological properties of two mixtures of perfluorononanoic acid (PFNA)/NaOH and perfluorodecanoic acid (PFDA)/NaOH were investigated in aqueous solutions. Interestingly, pH-sensitive polyhedral fatty acid vesicles were spontaneously formed in both systems, which were determined by freeze-fracture transmission electron microscopy (FF-TEM) measurements. Especially, a phase transition from faceted vesicles to the L3 phase with the increase of pH was observed in the PFNA/NaOH system while it was not observed in the PFDA/NaOH system. Differential scanning calorimetry (DSC) and wide angle X-ray scattering (WAXS) measurements confirmed that the bilayers of the faceted vesicles were in the crystalline station indicating that the crystallization of fluorocarbon chains was the main driving force for their formation. Besides, the two systems of faceted perfluorofatty acid vesicles exhibit interesting rheological properties, for instance, they showed high viscoelasticity and shear-thinning behaviour, and the elastic modulus (G') and viscous modulus (G'') of PFDA/NaOH vesicles were much higher than those of PFNA/NaOH vesicles. Conversely, the solution of the L3 phase with fluid bilayers did not present viscoelastic properties. Therefore, the viscoelastic properties of vesicles resulted from the crystalline fluorinated alkyl chains with high rigidity at room temperature and the dense packing of vesicles. As far as we know, such faceted fatty acid vesicles formed from single-tailed perfluorinated surfactants have been rarely reported. Our work successfully constructs polyhedral fatty acid vesicles and proposes their formation mechanism, which should be a great advance in the fundamental research of fatty acid vesicles.

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Polyhedral vesicles with crystalline bilayers formed from catanionic surfactant mixtures of fluorocarbon and hydrocarbon amphiphiles

Cited by 17 publications

References 44 publications

A Light-Responsive Self-Assembly Formed by a Cationic Azobenzene Derivative and SDS as a Drug Delivery System

A Light-Responsive Self-Assembly Formed by a Cationic Azobenzene Derivative and SDS as a Drug Delivery System

Efficient Photodynamic Therapy against Gram-Positive and Gram-Negative Bacteria Using Rose Bengal Encapsulated in Metallocatanionic Vesicles in the Presence of Visible Light

Faceted fatty acid vesicles formed from single-tailed perfluorinated surfactants

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