Polyelectrolyte microgels based on poly-N-isopropylacrylamide: influence of charge density on microgel properties, binding of poly-diallyldimethylammonium chloride, and properties of polyelectrolyte complexes

Kleinen, Jochen; Richtering, Walter

doi:10.1007/s00396-011-2401-4

Cited by 39 publications

(40 citation statements)

References 57 publications

Supporting

Mentioning

Contrasting

Order By: Relevance

“…This data indicates that the aggregation of p(4-VP) microgels in aqueous solutions is pH dependant. Furthermore, the location of charged moieties at the surface and/or inside the microgel affects the aggregation of microgels at different pH values [46][47][48]. It is expected that when they are located at the surface of the microgel, the pH-dependent ionization will lead to a good interaction of the particles especially at the surface.…”

Section: Aggregation Of the P(4-vp) Microgels In Watermentioning

confidence: 98%

Surface activity of amphiphilic cationic pH-responsive poly(4-vinylpyridine) microgel at air/water interface

Şahiner

Atta

Yasar

et al. 2015

Colloids and Surfaces A: Physicochemical and Engineering Aspect

View full text Add to dashboard Cite

Section: Aggregation Of the P(4-vp) Microgels In Watermentioning

confidence: 98%

Surface activity of amphiphilic cationic pH-responsive poly(4-vinylpyridine) microgel at air/water interface

Şahiner

Atta

Yasar

et al. 2015

Colloids and Surfaces A: Physicochemical and Engineering Aspect

View full text Add to dashboard Cite

“…In semi‐IPN, there was hydrogen bond between CONH groups of PNIPAM network and COOH groups of PAAc chains. The hydrogen bond was stronger at higher cross‐linked network and was able to enhance the difficulty for the dissociation of H + , leading to an increase in the p K 0 values . In addition, the p K 0 values for all semi‐IPN microspheres were higher than that of uncross‐linked PAAc polymer (p K 0 = 4.67,) which was due to the decrease in free energy of the unionized state stabilized by hydrogen bond …”

Section: Resultsmentioning

confidence: 96%

“…The intrinsic dissociation constant (p K 0 ) of the carboxyl group of PAAc chains can be determined as the pH value at α = 0.5 …”

Section: Methodsmentioning

confidence: 99%

Effects of Cross-Link Density on Structures and Properties of Dual-Sensitive Semi-Interpenetrating Polymer Networks Hydrogel Microspheres

Lai

Wang

et al. 2017

Macromol. Chem. Phys.

View full text Add to dashboard Cite

Semi-interpenetrating polymer network (semi-IPN) strategy is employed to fabricate uniform microspheres with temperature and pH dual-responsive behavior, which is composed of poly(Nisopropylacrylamide) and poly(acrylic acid) in the presence of N,N′-methylenebisacrylamide (MBA) as the cross-linker. The influences of MBA amount (M m ) on the structures and properties of the microspheres are investigated in terms of particle size, surface morphology, pH sensitivity, and thermo-sensitivity with low critical solution temperature in the range M m = 2.5-15%. Additionally, functional group distributions in the microspheres are probed by titration and employing the Henderson-Hasselbalch equation. The results show that all the properties strongly change depending on M m . Based on transmission electron microscopy and confocal laser scanning microscopy measurements, and these properties, the M m -induced changes in the structures of the semi-IPN microspheres are discussed. body, the hydrogels that respond to pH and temperature simultaneously have attracted significant attention. Poly(N-isopropylacrylamide) (PNIPAM) is one of the most extensively studied thermo-sensitive polymers, which can exhibit lowest critical solution temperature (LCST) at ≈32 °C close to human body temperature. To obtain the pH-responsive behavior of PNIPAM-based hydrogels, the formation of semi-interpenetrating polymer network (semi-IPN) has been proved to be a useful method. In 2001, Lee et al. prepared thermo-and pH-sensitive semi-IPN hydrogels composed of PNIPAM and alginate by cross-linking with calcium ions. [2] Subsequently, many efforts were devoted to prepare the pH/temperature dual-sensitive hydrogels based on PNIPAM and other polymers with semi-IPN structure, such as chitosan, poly(acrylic acid) (PAAc), and poly(aspartic acid) (PAS). [3][4][5] The resultant hydrogels exhibited improved temperature and pH responsiveness.However, the slow response rate of macroscopic semi-IPN hydrogels was still a drawback, which limited their further application in bioengineering. Considering the

show abstract

“…[9][10][11][12][13][14][15][16] Of these polymers, often called stimuli responsive polymers, poly (Nisopropylacrylamide) (pNIPAm) is by far the most extensively studied. 1, [17][18][19][20][21][22][23][24][25][26][27][28][29][30][31][32][33][34][35] PNIPAm is fully soluble in water at a temperature < 32 °C, existing as a fully solvated random coil while it transitions to a desolvated globule at T > 32 °C. 36 Likewise, pNIPAm-based polymer networks are responsive to temperature (thermoresponsive), transitioning from swollen to deswollen as the temperature of the water they are exposed to increases to > 32 °C.…”

Section: Introductionmentioning

confidence: 99%

Responsive polymers for biosensing and protein delivery

Islam

Gao

et al. 2014

J. Mater. Chem. B

View full text Add to dashboard Cite

show abstract

Polyelectrolyte microgels based on poly-N-isopropylacrylamide: influence of charge density on microgel properties, binding of poly-diallyldimethylammonium chloride, and properties of polyelectrolyte complexes

Cited by 39 publications

References 57 publications

Surface activity of amphiphilic cationic pH-responsive poly(4-vinylpyridine) microgel at air/water interface

Surface activity of amphiphilic cationic pH-responsive poly(4-vinylpyridine) microgel at air/water interface

Effects of Cross-Link Density on Structures and Properties of Dual-Sensitive Semi-Interpenetrating Polymer Networks Hydrogel Microspheres

Responsive polymers for biosensing and protein delivery

Contact Info

Product

Resources

About