Polyelectrolyte Complex (PEC) film based on chitosan as potential edible films and their antibacterial activity test

Ismillayli, Nurul; Andayani, I Gusti Ayu Sri; Honiar, Ruru; Mariana, Baiq; Sanjaya, Rochmad Kris; Hermanto, Dhony

doi:10.1088/1757-899x/959/1/012009

Cited by 8 publications

(3 citation statements)

References 17 publications

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“…Therefore, we hypothesized that the increased antibacterial effect of Chit30/AF-Pect (5 : 1) sponges compared to original polymers may be due to the formation of Schiff bases with imine groups (─RC═N─) from the interaction between chitosan's amino groups and oxidized pectin's aldehyde groups that enhances the positive charge of chitosan [85,86]. Similar results were reported for interpolyelectrolyte complexes of poly(acrylic acid)-chitosan [87], chitosan-alginate, chitosan-κ-carrageenan [88], and chitosan-oxidized pectin [51]. These polyelectrolyte complexes exhibited higher antibacterial activity against P. aeruginosa, P. oleovorans, and E. coli, S. aureus, and B. subtilis and S. aureus, respectively, than the original chitosan.…”

Section: Resultssupporting

confidence: 58%

Design of Highly Porous Materials Based on Chitosan/Pectin Interpolyelectrolyte Complex for Wound Healing Application

Kraskouski,

Mashkin,

Kulikouskaya

et al. 2024

Advances in Polymer Technology

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Interpolyelectrolyte complexes (IPECs) of polysaccharides are multifunctional polymer materials that improve the mechanical and physicochemical properties of individual polysaccharides. In this study, highly porous (>90%) materials based on IPECs of versatile natural polysaccharides, chitosan (30 and 1,200 kDa) and pectin, are obtained by freeze-drying technique. To enhance the interaction between chitosan and pectin macromolecules, the latter are chemically functionalized with dialdehyde groups. The chitosan-/aldehyde-functionalized pectin (Chit/AF-Pect) polyelectrolyte complex sponges obtained are characterized using SEM, FTIR spectroscopy, and TGA. The swelling capacity study reveals a higher swelling ratio of IPEC sponges with an increase in both the molecular weight and content of chitosan: for Chit30/AF-Pect, the swelling ratio rises from 327% to 480%, while for Chit1200/AF-Pect, from 681% to 1,066%. Additionally, the in vitro degradation test demonstrates higher stability of Chit1200/AF-Pect sponges in comparison with those of Chit30/AF-Pect: after 4 days of incubation, the weight losses are found to be 9%–16% and 18%–41%, respectively. The cytotoxicity study shows that Chit30/AF-Pect sponges are noncytotoxic, with cell viability values >70%. Furthermore, the Chit30/AF-Pect sponges, obtained at chitosan:pectin weight ratio of 5:1, exhibit bactericidal activity against Escherichia coli BIM B-984 G, Pseudomonas aeruginosa BIM B-807 G, Staphylococcus aureus BIM B-1841, and slightly inhibit the growth of Enterococcus faecalis BIM B-1530 G. These findings indicate that the obtained Chit30/AF-Pect sponges can be used to create wound dressings for wound healing applications.

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Section: Resultssupporting

confidence: 58%

Design of Highly Porous Materials Based on Chitosan/Pectin Interpolyelectrolyte Complex for Wound Healing Application

Kraskouski,

Mashkin,

Kulikouskaya

et al. 2024

Advances in Polymer Technology

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“…Because of the electrostatic attraction between the polycationic chitosan and the polyanionic polysaccharides, it is possible to form polyelectrolyte complexes. Generally, it has been found that polyelectrolyte complexes (PEC) have better physico-mechanical properties than its constituent polymers due to its tighter microstructure [ 136 ].…”

Section: Introductionmentioning

confidence: 99%

“…PEC have the ability to be used in matrices, beads, microparticle and nanoparticle systems, and microspheres and can be used as film coating [ 136 , 137 ], being used in drug delivery systems.…”

Section: Introductionmentioning

confidence: 99%

Factors Influencing the Antibacterial Activity of Chitosan and Chitosan Modified by Functionalization

Ardean

Davidescu

Nemeş

et al. 2021

IJMS

226

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The biomedical and therapeutic importance of chitosan and chitosan derivatives is the subject of interdisciplinary research. In this analysis, we intended to consolidate some of the recent discoveries regarding the potential of chitosan and its derivatives to be used for biomedical and other purposes. Why chitosan? Because chitosan is a natural biopolymer that can be obtained from one of the most abundant polysaccharides in nature, which is chitin. Compared to other biopolymers, chitosan presents some advantages, such as accessibility, biocompatibility, biodegradability, and no toxicity, expressing significant antibacterial potential. In addition, through chemical processes, a high number of chitosan derivatives can be obtained with many possibilities for use. The presence of several types of functional groups in the structure of the polymer and the fact that it has cationic properties are determinant for the increased reactive properties of chitosan. We analyzed the intrinsic properties of chitosan in relation to its source: the molecular mass, the degree of deacetylation, and polymerization. We also studied the most important extrinsic factors responsible for different properties of chitosan, such as the type of bacteria on which chitosan is active. In addition, some chitosan derivatives obtained by functionalization and some complexes formed by chitosan with various metallic ions were studied. The present research can be extended in order to analyze many other factors than those mentioned. Further in this paper were discussed the most important factors that influence the antibacterial effect of chitosan and its derivatives. The aim was to demonstrate that the bactericidal effect of chitosan depends on a number of very complex factors, their knowledge being essential to explain the role of each of them for the bactericidal activity of this biopolymer.

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Preparation of pH test strip based on immobilized Tectona grandis L. leaf extract on the alginate-chitosan membrane

Ismillayli¹,

Juniharti²,

Hadiyati³

et al. 2021

International Conference on Energy and Environment (Icee 2021)

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Polyelectrolyte Complex (PEC) film based on chitosan as potential edible films and their antibacterial activity test

Cited by 8 publications

References 17 publications

Design of Highly Porous Materials Based on Chitosan/Pectin Interpolyelectrolyte Complex for Wound Healing Application

Design of Highly Porous Materials Based on Chitosan/Pectin Interpolyelectrolyte Complex for Wound Healing Application

Factors Influencing the Antibacterial Activity of Chitosan and Chitosan Modified by Functionalization

Preparation of pH test strip based on immobilized Tectona grandis L. leaf extract on the alginate-chitosan membrane

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