Polydopamine-coated curdlan hydrogel as a potential carrier of free amino group-containing molecules

Chemically induced strengthening of curdlan alkylcarbamate thermoplastics

“…After repeating the same process twice, the precipitate was collected and dried in vacuo at 70°C for 3 h to obtain a mixed ester of CrdC(Hex)E(Me) (1430 mg, 88%). Gel permeation chromatography (GPC): M n = 6.2 × 10, 5 M w / M n = 2.0, DP = 1399; 1 H NMR (400 MHz, CDCl 3 , δ): 0.70–1.01 (m, 3H × 2.2; CH 3 ), 1.09–1.88 (m, 8H × 2.2; CH 2 ), 1.93–2.20(m, 3H × 0.8;CH 3 ), 2.33–3.73 (m, 2H × 2.2; CH 2 ), 2.33–5.21 (m, 7H; CH); IR (KBr): ν = 3324, 2925, 1715, 1521, 1238 cm −1 .…”

“…The successive reaction treatments gave a mixed ester, curdlan dodecylcarbamate and heptanoate (CrdC(Dod)E(Hex)) (1508 mg, 88%). GPC: M n = 10.0 × 10, 5 M w / M n = 1.6, DP = 1356; 1 H NMR (400 MHz, CDCl 3 , δ): 0.70–1.01 (m, 3H × 2.3 + 3H × 0.7; CH 3 ), 1.09–1.88 (m, 8H × 2.3; CH 2 ), 2.40–2.57(m, 2H × 0.7;CH 2 ), 2.33–3.73 (m, 2H × 2.3; CH 2 ), 2.33–5.21 (m, 7H; CH); IR (KBr): ν = 3321, 2925, 1715, 1521, 1238 cm −1 .…”

“…Commercially available curdlan β‐1,3‐glucan, 1 has been used as a gelling and thickening agent in food additives, 2 packing films, 3,4 and drug carriers, 5,6 because of its low toxicity, ability to gel upon heating, and modifiable properties. Compared to cellulose, curdlan is easily soluble in alkaline aqueous solutions and organic solvents such as formic acid and dimethyl sulfoxide.…”

Engineering bioactive synthetic polymers for biomedical applications: a review with emphasis on tissue engineering and controlled release

“…The experimental evidence indicates that coating SyP-electospun scaffolds with pDA is an effective strategy for promoting cell remodeling, although the underlying mechanism is not fully understood. The ability of pDA to confer hydrophilicity to surfaces, 66,71,72 to bind bioactive molecules, [73][74][75] and to (presumably) trigger cell-signaling pathways [76][77][78] may provide elements that can explain the observed outcomes.…”

Collagen-Sealed Polyester Vascular Prostheses Functionalized by Polycatecholamine Coatings

“…We have recently reported the deposition of polymerized L-DOPA (PLD) on natural curdlan (β-1,3-glucan) and synthetic polyester fibers (of complex 3D structure), followed by gentamicin immobilization on the coatings. Both curdlan and polyester fibers, coated with PLD, exhibited higher antibiotic binding yield and antimicrobial activity in comparison with the same fibers coated with PDA [ 19 , 20 , 21 ]. It was also shown that human endothelial cells proliferated better on PLD-coated polyester fibers than on the pristine ones and that this modification reduced the toxicity against Danio rerio embryos [ 19 ].…”