Polydextrose in Lipid Metabolism

Putaala, Heli

doi:10.5772/51791

Cited by 4 publications

(6 citation statements)

References 154 publications

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“…Due to its complex structure and to the nature of its glycosidic bonds, PDX is resistant to mammalian digestive enzymes in the upper gastrointestinal tract. For this reason, PDX reaches the colon intact where it is partially fermented by gut microbiota, stimulating selectively target bacterial groups [84,85,88]. These two characteristics, indigestibility and selective fermentability, support that the PDX has been identified as a source of prebiotic fiber with several healthpromoting effects [89], including:…”

Section: Prebiotic Effectsmentioning

confidence: 92%

“…Recently, other methods have been explored as the synthesis by microwave irradiation [83]. PDX is composed of a mixture of glucose oligomers, with an average degree of polymerization (DP) of 12, ranging from DP 2-120 [84,85] and contains all different combinations of α-and β-(1,2), (1,3), (1,4), and (1,6) glycosidic linkages, but α-( 1,6) linkages are predominant [85,86]. PDX is regarded as a resistant polysaccharide [87] and it is widely used in the food industry as a low-energy bulking agent (1 kcal/g) and as a sugar or fat replacer [86].…”

Section: Polydextrose (Pdx)mentioning

confidence: 99%

“…• Modulation of the lipid metabolism, decreasing the total cholesterol and LDL cholesterol and increasing HDL cholesterol [84].…”

Section: Prebiotic Effectsmentioning

confidence: 99%

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Pectic Oligosaccharides and Other Emerging Prebiotics

Míguez¹,

Gómez²,

Gullón³

et al. 2016

Probiotics and Prebiotics in Human Nutrition and Health

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Abstract" prebiotic is a selectively fermented ingredient that results in specific changes in the composition and/or activity of the gastrointestinal microbiota, thus conferring benefit s upon host health. The most widely accepted prebiotics are lactulose, inulin, fructooligosaccharides FOS , galactooligosaccharides GOS , and the human milk oligosaccharides HMO . However, there is a growing list of potential prebiotics although the evidence for these, especially in humans, is not as well established as for FOS and GOS. Some of them are already commercialized but others such as polydextrose PDX , pectic oligosaccharides POS , bacterial exopolysaccharides EPS , polysaccharides derived from algae and sugar alcohols are still in the early stages of development. This chapter summarizes the scientific literature regarding the manufacture and the evaluation of the properties of this group emerging prebiotics . Keywords: emerging prebiotics, pectic oligosaccharides, polydextrose, algae-derived oligosaccharides, bacterial exopolysaccharides, sugar alcohols . IntroductionThe consumption of prebiotics is being specially considered as a good health-improving strategy they have been recently defined as nondigestible compounds that through its metabolization by microorganisms in the gut, modulate the composition and/or the activity of the gut microbiota, thus conferring physiological benefit effects on the host health [ ].The microbial communities that inhabit the human intestinal tract constitute a complex association, comprising more than species and around microorganisms, mainly anaerobic > . % . levels of microorganisms and the main bacterial groups. "long the jejunum, and particularly in the ileum, there is a gradual increase in the number and diversity of bacteria, and finally, the majority of gastrointestinal microbes are housed in the colon [ ]. However, scientific works on this field suggest that the gut microbiota is not only a simply collection of microorganisms, but also reflects an interrelationship between the different groups that might work together for the benefit of the host [ ]. In addition, the microbiota also establishes a close symbiosis with the host humans provide the nutrients and the appropriate conditions for its development, and it performs three essential primary functions metabolic, trophic, and defensive [ ]. In fact, there is a long list of pathologies which are linked to the alteration of the gut microbiota, including hepatic encephalopathy, diarrhea, diabetes, obesity, colon cancer, I"S, I"D, gastrointestinal infections, and necrotizing enterocolitis [ , ].The composition of the gut microbiota is influenced by a variety of factors that include i the microbial species which are acquired at birth, ii host genetics, iii age [ ], iv diseases and antibiotic usage [ , ], v the stress [ ], and vi the diet. In fact, the diet is probably the most important factor and several studies are focused on the modulation of the gut microbiota by the consumption of functional foods, such as prebiotics [ ].For c...

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Section: Prebiotic Effectsmentioning

confidence: 92%

Section: Polydextrose (Pdx)mentioning

confidence: 99%

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Pectic Oligosaccharides and Other Emerging Prebiotics

Míguez¹,

Gómez²,

Gullón³

et al. 2016

Probiotics and Prebiotics in Human Nutrition and Health

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“…Los AGCC, tras ser producidos, actúan directamente en el hígado, inhibiendo el metabolismo del colesterol y la lipogénesis. Cabe resaltar que algunos estudios mencionan que el contenido de las bifidobacterias tiene una relación positiva con el aumento del HDL y que la polidextrosa tiene como efecto en el organismo la promoción del crecimiento de esas bacterias 7,27,28 . Si bien el actual estudio no ha encontrado efectos de la polidextrosa en la reducción del colesterol total y LDL, los niveles altos de HDL ya son un importante factor protector para el riesgo de enfermedades cardiovasculares 27,29,30 .…”

Section: Parámetrosunclassified

“…Esos efectos fueron también verificados en las dosificaciones de la glucosa sérica del actual estudio, mostrando que los animales de los grupos HC2%P y HC6%P presentaron menores tasas de azúcar en la sangre. Además, la polidextrosa tiene un índice glucémico muy bajo 7,27 , siendo también una de las explicaciones del menor contenido de glucosa sanguínea encontrado en el grupo suplementado con el 6,0% de polidextrosa.…”

Section: Parámetrosunclassified

El consumo de la polidextrosa previene la obesidad y sus comorbilidades en ratas alimentados con dieta hipercalórica

Souza

Zampieri

et al. 2020

Rev. chil. nutr.

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RESUMEN El objetivo de este trabajo fue evaluar el efecto de las diferentes concentraciones de polidextrosa en la prevención de la obesidad y sus comorbilidades, en ratas alimentados con dieta hipercalórica. Se utilizaron ratas machos Wistar, repartidos en 4 grupos: Grupo control (HC) y 3 grupos que recibieron dieta hipercalórica con suplementación del 2%, 4% y 6% de polidextrosa (HC2%P, HC4%P y HC6%P respectivamente). La dieta hipercalórica utilizada fue la del tipo de cafetería para inducir la obesidad. Se midió peso corporal e ingesta de la dieta, se realizaron pruebas de tolerancia a la glucosa y a la insulina. Los animales fueron sometidos a eutanasia para toma de muestra de sangre medidas antropométricas y pesaje de órganos y tejidos. La polidextrosa disminuyó significantemente el peso, la grasa corporal, la glicemia, los triglicéridos, la intolerancia a la glucosa y la resistencia a la insulina, y aumentó los niveles del colesterol HDL. Se concluye que el consumo de polidextrosa redujo las complicaciones derivadas de la obesidad en ratas alimentados con dieta hipercalórica, siendo éste un potencial tratamiento para el control de la obesidad, la diabetes tipo II y las enfermedades cardiovasculares.

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