Abstract:Background
Lead (Pb) is toxic and cause many adverse clinical outcomes in children and adult, however, polydatin (PD) is a natural product from plants with reported antioxidative, neuroprotective and inflammatory properties. This study investigated the role of polydatin on lead-induced behavioural deficits, oxidative stress and inflammatory damages in D. melanogaster. D. melanogaster (Harwich strain, 1 to 3 days old) were orally administered lead acetate (PbAc) (0, 50, 100, 250 and 500 µM/5g diet) and PD (0, … Show more
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