Polycystic ovaries and herbal remedies: A systematic review

Abstract

Objective: Polycystic ovary syndrome (PCOS) is an endocrine disorder that affects one in every 15 women worldwide. This disorder is mainly characterized by increased levels of male hormones (androgens), acne, and hirsutism, and can lead to long-term insulin resistance, miscarriage, or even infertility in women. PCOS is a disorder that can be treated with natural and allopathic remedies that work against the PCOS mechanism. The present study reviews previous studies on the treatment of PCOS using natural drugs.Methods: The data in this study were collected from articles published in reputable databases including ScienceDirect, PubMed, Google Scholar, and SID in the field of medicinal plants from 1990 to 2021.Results: A review of the literature showed that plants such as aloe vera and chamomile improve fertility by increasing the number of ovarian follicles. Besides, Vitex agnus-castus and octane reduce hirsutism by reducing testosterone and androgen levels. It was also shown that liquorice, ginseng, cinnamon, and de chiro Inositol improve the adverse effects of diabetes caused by PCOS by lowering lipid and blood glucose levels. Moreover, Stachys lavandulifolia and fennel are effective in changing endometrial tissue parameters in PCOS by reducing estrogen and hyperplasia.Conclusions: Various studies have shown that herbal medicines can improve PCOS symptoms in women with minimal side effects but a longer treatment cycle.

The Role of Oxidative Stress on Cardiovascular Properties of the Androgen- Induced PCOS in Female Rats

“…Impact of management of Glyrrhiza Glabra L. root extract on blood sugar, was shown in Table 3, which indicate that the root wad significantly decreases the level of glucose and this result was conformable with other study [35]. The action of providing licorice root hydroalcoholic extract on blood serum glucose, TG, and TC concentration had been studied in 50 Sprague rats on PCOS, which they founded that the letrozole group had higher blood serum glucose than normal control [p˂0.05].…”

The effects of flaxseed or its oil supplementations on polycystic ovary syndrome: A systematic review of clinical trials

“…In recent years, the use of natural compounds and herbs in the PCOS women (Manouchehri et al, 2022). Intervention with vitamin D (Miao, Fang, Chen, & Zhang, 2020), vitamin E (Tefagh et al, 2022), omega-3 fatty acids (J.…”

“…In recent years, the use of natural compounds and herbs in the control and treatment of PCOS has been promising (Kwon, Cho, & Park, 2020; Moini Jazani, Nasimi Doost Azgomi, Nasimi Doost Azgomi, & Nasimi Doost Azgomi, 2019). A recent systematic review stated that natural herbs such as aloe vera and chamomile improve fertility; Vitex agnus‐castus and octane reduce hirsutism; liquorice, ginseng, cinnamon, myo‐inositol improve insulin sensitivity; and Stachys lavandulifolia and fennel are effective in endometrial status in PCOS women (Manouchehri et al, 2022). Intervention with vitamin D (Miao, Fang, Chen, & Zhang, 2020), vitamin E (Tefagh et al, 2022), omega‐3 fatty acids (J.…”

Evaluation of the anti‐PCOS Potential of Ethanolic Extract of Ocimum Gratissimum (Linn.) Leaf in Letrozole‐Induced Polycystic Ovarian Syndrome in Wistar Rats

“…[16][17][18] Natural products like pheoniflorin, catechins, licorice, and isosorbol have been shown in numerous scientific investigations to be promising as an alternate treatment for PCOS. [19][20][21][22][23][24][25][26] Treatment of syndromes with signs and symptoms linked to one another and with a disease is one area of medical practice where doctors frequently encounter difficulty. Polycystic Ovarian Syndrome (PCOS), also referred to as Stein-Leventhal syndrome, is a common endocrine disorder that impacts 12-21 % of women in their reproductive years.…”

“…for female fertility and menstruation [16–18] . Natural products like pheoniflorin, catechins, licorice, and isosorbol have been shown in numerous scientific investigations to be promising as an alternate treatment for PCOS [19–26] …”