Polycystic Ovarian Disease

Abstract

Introduction: Poly Cystic Ovarian Disease (PCOD) is probably one of the most commonendocrinological disorders amongst the women during their reproductive years. Using USG criteria only 20-33% ofapparently healthy women in childbearing period, have been found to have PCOD in population study. Whereasprevalence of 4-10% in women of reproductive age is commonly reported when the diagnosis is based on clinical,biochemical and US scan features. Objective:-Diagnosis and management of polycystic ovarian disease. Setting SeyalMedical Centre, Multan. Duration From January 2002 to December 2003. Material and Methods: Sample size: 200patients. Results: Most of he patients were in the age group of 21-30 years. The youngest patient was of 17 years andeldest was of 42 years. Majority of the women were nulliparous or of low parity comprising 92% of cases. Thecommonest symptom was menstrual disorder in 168 Patients (84%). Ultrasound is very helpful for diagnosis of POD.About 80% of patients were diagnosed as PCOD on ultrasound. There is increased level of LH in 72% patients, 8%have raised prolactin levels. All patients were first treated with clomiphene citrate while surgical treatment is done inonly 30% of cases. GnRH analogue and purified FSH were not used because they are quite expensive. Conclusion:PCOD is found to be one of the commonest problem in reproductive years of life. Clomiphene citrate is first linetreatment in PCOD for infertility. Laparoscopic drilling has very good results especially in clomiphene resistant cases.

Clinical and Radiological Profile of Patients with Polycystic Ovary Syndrome

“…In the present study, LH levels were elevated in more than 50% of participants, compared to 40% in Balen et al and 72% in the Multan study. 9,14 Prolactin was slightly raised in 3% of patients compared to 8% in the study at Multan. 14 In a study by Aziz et al in 2001 proportion of obese patients was also 30%.…”

“…9,14 Prolactin was slightly raised in 3% of patients compared to 8% in the study at Multan. 14 In a study by Aziz et al in 2001 proportion of obese patients was also 30%. 16 Another research done in Rawalpindi found that 58% of patients had elevated HDL levels, whereas 12% and 21% of patients had elevated cholesterol and triglyceride thresholds.…”

“…The findings of the current research are corroborated by several other studies. 9,11,14 In 1.61% of PCOS individuals, which was nearly the same as the frequency in the general population, recurrent miscarriage was a presenting characteristic. This study's findings are consistent with other studies' findings in that recurrent miscarriages were not more common in PCOS individuals.…”