Polycystic Disease of the Kidney and Liver in the Cairn Terrier

Abstract

Abstract. Three related puppies with abdominal distention caused by nephromegaly and hepatomegaly had gross and histologic lesions in the kidney and liver similar to polycystic disease of children. Both kidneys were enlarged and reniform, and contained multiple fusiform or cylindrical cysts lined by cuboidal epithelium radiating through the cortex and medulla.

Congenital cystic disease of the liver in seven dogs

“…The liver and kidney lesions in our case 7 and in the Cairn terrier pups described by McKenna and Carpenter (1980) are basically identical. Both showed fusiform dilatation of the intrahepatic and extrahepatic bile ducts and polycystic kidneys type I.…”

“…Table 1 (Ishak and Sharp, 1979;Hadad et al, 1976). Whereas congenital dilatation of the bile ducts types I, II and III, solitary cysts of the liver and the adult type of polycystic disease of the liver are well described entities, considerable overlap has been noted between the childhood type of polycystic disease of the liver, congenital hepatic fibrosis and congenital dilatation of the bile ducts types IV and V (Murray-Lyon, Ockenden and Williams, 1973;Ishak and Sharp, 1979;Nakanuma, Terada, Ohta, Kurachi and Matsubara, 1982). Congenital dilatation of the bile duct types I, II and III has not been described in the dog.…”

Serum Amyloid A (SAA) as a Biomarker of Chronic Infection Due to Boat Strike Trauma in a Free-ranging Florida Manatee (Trichechus manatus latirostris) with Incidental Polycystic Kidneys

“…), ferrets (Mustela putorius furo), rats (Rattus sp. ), Persian cats (Felis catus), and dogs (Canis domesticus;McKenna and Carpenter, 1980;McAloose et al, 1998;Maurer et al, 2004). In humans, this autosomal dominant condition is expressed grossly as bilaterally enlarged kidneys of which the external and cut surfaces appear to be composed solely of variably-sized cysts.…”

Juvenile Nephropathy in a Boxer Dog Resembling the Human Nephronophthisis-Medullary Cystic Kidney Disease Complex

“…A number of renal pathologies with a cystic component have been described in dogs including: Polycystic Kidney Disease (PKD) [25,27,[32][33][34]; juvenile nephropathy (JN) [5,26,35]; renal dysplasia [12,28,30,31,36,42]; medullary sponge kidney [2]; glomerulocystic kidney disease (GCKD) [4,38,46]; primary renal neoplasia such as hereditary multifocal renal cystadenocarcinomas and nodular dermatofibrosis (RCND) [3,19,20,29,48]; renal cystadenoma [23], and acquired cysts [37]. PKD is a genetic disorder characterized by bilateral renal cysts of varying size and number distributed uniformly in the cortex and medulla [32].…”