Polycyclic aromatic hydrocarbons in surface water and bed sediments of the Hungarian upper section of the Danube River

Nagy, Andrea Szabó; Simon, Gábor; Szabó, J.; Vass, István

doi:10.1007/s10661-012-2892-6

Cited by 42 publications

(11 citation statements)

References 28 publications

Supporting

Mentioning

Contrasting

Order By: Relevance

“…Pyr has been found at very high concentrations in sediments, sometimes exceeding 10 µg/g of sediment (see Table 1) from areas heavily impacted by PAHs. Indeed, Pyr is often amongst the most abundant of PAHs in sites affected by creosote or pyrogenic inputs (Nagy et al 2013;Kimbrough and Dickhut 2006;Wang et al 2001). Moreover, Pyr has been reported to greatly accumulate and to be efficiently metabolized by phase I and phase II enzymes in fish ELS (Honkanen et al 2008;Petersen and Kristensen 1998).…”

Section: Introductionmentioning

confidence: 99%

Transcriptional responses and embryotoxic effects induced by pyrene and methylpyrene in Japanese medaka (Oryzias latipes) early life stages exposed to spiked sediments

Barjhoux

Cachot

Gonzalez

et al. 2014

Environ Sci Pollut Res

View full text Add to dashboard Cite

Japanese medaka (Oryzias latipes) embryos were exposed to sediments spiked with environmental concentrations (300 and 3,000 ng/g dry weight) of pyrene (Pyr) and methylpyrene (MePyr) throughout their development. Embryotoxicity, teratogenicity, and transcriptional responses (qRT-PCR) were analyzed in embryos and newly hatched larvae. The genotoxicity of the two polycyclic aromatic hydrocarbons (PAHs) was also tested in prolarvae using the comet assay. Exposure to each compound had a clear impact on embryonic development and resulted in several teratogenic effects, including cardiovascular injuries, reduced absorption of yolk sac reserves, and jaw and spinal deformities. Interestingly, the overall toxic effects of Pyr and MePyr considerably overlapped those induced following dioxin exposure. qRT-PCR analysis revealed the transcriptional induction of genes involved in mitochondrial energetic metabolism (coxI), xenobiotic biotransformation (cyp1a), and cell cycle regulation (wnt1) by the two PAHs. MePyr also activated cell cycle arrest (p53), oxidative DNA damage repair (ogg1), and retinoid-mediated (raldh2 and rarα1) gene transcription. DNA damage was not found to be significantly increased following Pyr and MePyr exposure. The lack of significant genotoxic effect in comparison to the control might be the consequence of the efficient onset of DNA damage repair mechanisms as suggested by ogg1 gene transcription upregulation. Results reported in the present study have brought new insights into the modes of action of Pyr, and the effects of MePyr exposure have been investigated in fish ELS for the first time.

show abstract

Section: Introductionmentioning

confidence: 99%

Transcriptional responses and embryotoxic effects induced by pyrene and methylpyrene in Japanese medaka (Oryzias latipes) early life stages exposed to spiked sediments

Barjhoux

Cachot

Gonzalez

et al. 2014

Environ Sci Pollut Res

View full text Add to dashboard Cite

show abstract

“…WFD categorized DEHP as PSs (WFD, 2013) due to the various factors, such as high detection frequency and persistence in environmental compartments (Luo et al, 2014) and augmented toxicity and bioaccumulation in aquatic species (Sousa et al, 2017). PAHs were also declared as PSs by ATSDR and WFD a long-time ago (ATDSR, 1995;WFD, 2000) and PAHs exhibited fused aromatic ring structure with mutagenic and carcinogenic properties, long-half lives and potential to generate heteroaromatic hydrocarbons after chemical reactions (Kafilzadeh, 2015;Nagy et al, 2013).…”

Section: Existing Regulations For Priority Substances (Pss) and Contamentioning

confidence: 99%

Environmental Concerns and Toxicogenetic Endpoints of Priority Substances (PSs) and Contaminants of Emerging Concerns (CECs): A Comprehensive Review

Liu¹,

Junaid²,

Hamid³

et al. 2018

American Journal of Environmental Sciences

View full text Add to dashboard Cite

Priority Substance (PSs) and Contaminant of Emerging Concerns (CECs) exhibited a wide range of environmental and public health concerns worldwide. This review summarized the documented studies related to the current surface water occurrence, spatial distribution, ecological risks and toxicity of selected PSs, such as polycyclic aromatic hydrocarbons (PAHs) and CECs, such as Di(2-Ethylhexyl) Phthalate (DEHP) and Pharmaceuticals and Personal Care Products (PPCPs). The spatial distribution analysis revealed alarming levels of PAHs in the surface waters of Asian counties, e.g., 84210 ng L −1 in Gomti River, India, 29325 ng L −1 in Daya Bay, China and 1287 ng L −1 in Chenab River, Pakistan. As for DEHP, the highest concentrations of 13050 µg L −1 in Liao River, China, and 2306 µg L −1 in Rivers of Eastern Cape, South Africa were reported. These environmental levels of PAHs and DEHP were many folds higher than the surface water permissible levels devised by WHO and USEPA. Contrarily, the emerging PPCPs were reported in relatively lower levels in the surface waters globally, compared to that of PAHs and DEHP. Consistent with the environmental levels, PAHs and DEHP revealed alarming ecological risks in the surface water sources, compared to that of PPCPs. Regarding to the sources of PSs and CECs, PAHs emissions were mostly linked to the incomplete combustion of petroleum products, DEHP contamination was associated to its applications in consumption and production of plastic appliances and PPCPs emissions were largely related to the domestic and industrial effluents. As for toxic endpoints of PAHs, DEHP and PPCPs, all of these were reported to cause DNA damage, genotoxicity, reproductive toxicity, developmental toxicity and immunotoxicity, as revealed in reviewed in vitro/vivo studies. In addition, the current review also highlighted the existing environmental regulations to control the emissions of these pollutants to the environmental matrices. Taken together, this review concluded that despite the existing environmental regulations, the current levels of organic pollutants are still on rising, especially in Asian countries. Therefore, the strict implementation of the existing regulations is highly necessary to control these pollutants to ensure public health and ecological integrity.

show abstract

“…HPHAs were significantly more dominant in sediments than in water. High proportions of LPAHs are commonly dominant in the dissolved phase owing to their higher water solubility and vapor pressure compared with that of the HPAHs (Nagy et al 2013). This is because HPAHs are difficult to degrade and have high hydrophobic property, contributing to them to be accumulated in the sediments more readily (Luo et al 2008) (Parinos et al 2013).…”

Section: Composition Pattern Of Pahs In Particle and Dissolved Phasesmentioning

confidence: 99%

From headwaters to estuary: distribution, sources, and ecological risk of polycyclic aromatic hydrocarbons in an intensively human-impacted river, China

Zhen

Liu

et al. 2018

Environ Sci Pollut Res

View full text Add to dashboard Cite

Located in the Shandong Province, North China, the Xiaoqing River is heavily contaminated by industrial wastewater and domestic sewage. However, it plays a significant role with regard to irrigation for agriculture in the river basin. In this study, spatial distribution, sources, and the ecological risk of aqueous polycyclic aromatic hydrocarbons (PAHs) in the Xiaoqing River Basin were investigated from the headwaters to the estuary. Fifteen USEPA priority PAHs (except naphthalene) were quantified in water particulate and soluble phases and in sediment samples. Σ 15 PAHs concentrations in the sediment varied from 17.15 to 3808.01 ng/g dry weight (dw), with an average of 988.72 ng/g dw, suggesting severe pollution of the Xiaoqing River in comparison with other rivers worldwide. The composition of PAHs was characterized by the high abundance of 4-ring and 5ring PAHs in sediments and 2-ring and 3-ring PAHs in water. Industrial wastewater is a significant source of PAHs. In the river section, point source was the main factor affecting the distribution of PAHs, while in the estuary region, estuarine turbidity maximum zone (ETM), riverine flow and discharge, and its hydrodynamic parameters play more key roles on PAH levels. Molecular diagnostic ratios have proved that PAHs in sediments were derived from mixed sources, primarily a combination of several combustion processes. Toxicity equivalency concentrations (TEQs) and Ecological risk assessment by Sediment Quality Guidelines indicated that PAHs in sediments might have certain unfavorable effects on ecosystems in certain sites.

show abstract

Polycyclic aromatic hydrocarbons in surface water and bed sediments of the Hungarian upper section of the Danube River

Cited by 42 publications

References 28 publications

Transcriptional responses and embryotoxic effects induced by pyrene and methylpyrene in Japanese medaka (Oryzias latipes) early life stages exposed to spiked sediments

Transcriptional responses and embryotoxic effects induced by pyrene and methylpyrene in Japanese medaka (Oryzias latipes) early life stages exposed to spiked sediments

Environmental Concerns and Toxicogenetic Endpoints of Priority Substances (PSs) and Contaminants of Emerging Concerns (CECs): A Comprehensive Review

From headwaters to estuary: distribution, sources, and ecological risk of polycyclic aromatic hydrocarbons in an intensively human-impacted river, China

Contact Info

Product

Resources

About