Polycyclic aromatic compounds in urban air and associated inhalation cancer risks: A case study targeting distinct source sectors

Jariyasopit, Narumol; Tung, Phoebe; Su, Ky; Halappanavar, Sabina; Evans, Greg J.; Su, Yushan; Khoomrung, Sakda; Harner, Tom

doi:10.1016/j.envpol.2019.06.015

Cited by 52 publications

(40 citation statements)

References 46 publications

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“…A similar nding was also found by the comparison of PAHs in different areas in Indian, and the results showed that uoranthene in the industrial sites was signi cantly higher than those in commercial sites [17]. Other studies concluded that atmospheric uoranthene concentrations may have sources other than motor vehicles [18,19]. Fluoranthene may therefore be considered an important indicator of industrial emissions.…”

Section: Resultssupporting

confidence: 76%

Non-target screening of organic pollutants and target analysis of halogenated polycyclic aromatic hydrocarbons in the atmosphere around metallurgical plants by high-resolution GC/Q-TOF-MS

Yang

Zheng

et al. 2020

Preprint

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Background：The 16 priority polycyclic aromatic hydrocarbons (PAHs) issued by US Environmental protection agency are a major focus in atmosphere in previous studies. Much more PAH congeners or their substitutes could be produced during combustion or thermal industrial processes and released into the atmosphere. However, a full screening of various organic pollutants in air surrounding important industrial sources have not been conducted. Identifying and characterizing organic pollutants in air is essential to accurate risk assessment. This study conducted non-target screening of organic pollutants and simultaneous target analysis of emerging contaminants including 8 polychlorinated naphthalenes and 30 higher cyclic halogenated PAHs by high-resolution gas chromatography quadrupole time-of-flight mass spectrometry (GC/Q-TOF-MS) and applied to the air samples collected surrounding metallurgical plants. Emerging organic chemicals of high toxicity in air were identified.Results：We identified and characterized 187 organic chemicals categorized as PAHs, alkylated polycyclic aromatic compounds (PACs), heterocyclic PACs, and aliphatic hydrocarbons in atmosphere around industrial sources. Some of these identified chemicals, such as phthalic acid esters, dimethylbenz[a]anthracene, and hydroquinone with alkane substituents are of potential high toxicities and have not been the focus of previous studies of airborne contaminants. Moreover, hydroquinone with alkane substituents may be critical intermediates and precursors of an emerging contaminant- environmentally persistent free radicals. Thus, the presences of those identified highly toxic chemicals in the air merits attention. Moreover, 38 chlorinated and brominated PAHs as target compounds were accurately quantitated by using isotopic dilution method by application of GC/Q-TOF-MS, and the findings were similar to those of high-resolution magnetic mass spectrometry. Conclusion：In this study, both non-target screening of organic pollutants and target analysis of halogenated PAHs in air were achieved by GC/Q-TOF-MS. The method could be of significance for simultaneous analysis of those trace pollutants containing multiple congeners. Specific pollutants of potential high toxicity in atmosphere around industrial sources were identified. Those knowledge could be helpful for comprehensively recognizing the organic contaminants in air surrounding metallurgical plants and better understanding their potential health risks.

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Section: Resultssupporting

confidence: 76%

Non-target screening of organic pollutants and target analysis of halogenated polycyclic aromatic hydrocarbons in the atmosphere around metallurgical plants by high-resolution GC/Q-TOF-MS

Yang

Zheng

et al. 2020

Preprint

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show abstract

“…A similar finding was also found by the comparison of PAHs in different areas in India, and the results showed that fluoranthene in the industrial sites was significantly higher than those in commercial sites [17]. Other studies concluded that atmospheric fluoranthene concentrations may have sources other than motor vehicles [18,19]. Fluoranthene may therefore be considered an important indicator of industrial emissions.…”

Section: Aromatic Hydrocarbons In Air By Non-target Analysis Of Gc/q-supporting

confidence: 80%

Non-target screening of organic pollutants and target analysis of halogenated polycyclic aromatic hydrocarbons in the atmosphere around metallurgical plants by high-resolution GC/Q-TOF-MS

Yang

Wu²,

Zheng

et al. 2020

Environ Sci Eur

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Background: The 16 priority polycyclic aromatic hydrocarbons (PAHs) issued by US Environmental protection agency are a major focus in atmosphere in previous studies. Many more PAH congeners or their substitutes could be produced during combustion or thermal industrial processes and released into the atmosphere. However, a full screening of various organic pollutants in air surrounding important industrial sources has not been conducted. Identifying and characterizing organic pollutants in air is essential for accurate risk assessment. This study conducted non-target screening of organic pollutants and simultaneous target analysis of emerging contaminants including 8 polychlorinated naphthalenes and 30 higher cyclic halogenated PAHs by high-resolution gas chromatography quadrupole timeof-flight mass spectrometry (GC/Q-TOF-MS) and applied to the air samples collected surrounding metallurgical plants. Emerging organic chemicals of high toxicity in air were identified. Results: We identified and characterized 187 organic chemicals categorized as PAHs, alkylated polycyclic aromatic compounds (PACs), heterocyclic PACs, and aliphatic hydrocarbons in atmosphere around industrial sources. Some of these identified chemicals, such as phthalic acid esters, dimethylbenz[a]anthracene, and hydroquinone with alkane substituents are of potential high toxicities and have not been the focus of previous studies of airborne contaminants. Moreover, hydroquinone with alkane substituents may be critical intermediates and precursors of an emerging contaminant-environmentally persistent free radicals. Thus, the presence of those identified highly toxic chemicals in the air merits attention. Moreover, 38 chlorinated and brominated PAHs as target compounds were accurately quantitated by using isotopic dilution method by application of GC/Q-TOF-MS, and the findings were similar to those of high-resolution magnetic mass spectrometry. Conclusion: In this study, both non-target screening of organic pollutants and target analysis of halogenated PAHs in air were achieved by GC/Q-TOF-MS. The method could be of significance for simultaneous analysis of those trace pollutants containing multiple congeners. Specific pollutants of potential high toxicity in atmosphere around industrial

show abstract

“…Accordingly, numerous PAS studies have sought to estimate inhalation exposure and the health risk associated with exposure to airborne PAHs. 336,348,[361][362][363]439,526 This is typically done by summing the products of the concentration of carcinogenic PAHs with their relative potency factors in order to obtain an equivalent concentration of benzo[a]pyrene, which in turn can be converted into a chronic daily inhalation intake rate. Sometimes, a value for the cancer risk due to inhalation is derived as well.…”

Section: View Article Onlinementioning

confidence: 99%

Passive air sampling for semi-volatile organic chemicals

Wania

Shunthirasingham

2020

Environ. Sci.: Processes Impacts

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Polycyclic aromatic compounds in urban air and associated inhalation cancer risks: A case study targeting distinct source sectors

Cited by 52 publications

References 46 publications

Non-target screening of organic pollutants and target analysis of halogenated polycyclic aromatic hydrocarbons in the atmosphere around metallurgical plants by high-resolution GC/Q-TOF-MS

Non-target screening of organic pollutants and target analysis of halogenated polycyclic aromatic hydrocarbons in the atmosphere around metallurgical plants by high-resolution GC/Q-TOF-MS

Non-target screening of organic pollutants and target analysis of halogenated polycyclic aromatic hydrocarbons in the atmosphere around metallurgical plants by high-resolution GC/Q-TOF-MS

Passive air sampling for semi-volatile organic chemicals

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