Polyclonality Strongly Correlates with Biologic Outcomes and Is Significantly Increased Following Improvements to the Phase 1/2 HGB-206 Protocol and Manufacturing of Lentiglobin for Sickle Cell Disease (SCD; bb1111) Gene Therapy (GT)

Walters, Mark C.; Thompson, Alexis A.; Mapara, Markus Y.; Kwiatkowski, Janet L.; Krishnamurti, Lakshmanan; Aygün, Banu; Kasow, Kimberly A.; Rifkin-Zenenberg, Stacey; Schmidt, Manfred; Pierciey, Francis J.; Whitney, Dustin; Rogers, Cynthia; Nnamani, Mauris C.; Foos, Marianna; Miller, Alex; Zhang, Xinyan; Lynch, Jessie; Kanter, Julie; Tisdale, John F.; Bonner, Melissa

doi:10.1016/s2666-6367(22)00178-6

Transplantation and Cellular Therapy

2022

DOI: 10.1016/s2666-6367(22)00178-6

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Polyclonality Strongly Correlates with Biologic Outcomes and Is Significantly Increased Following Improvements to the Phase 1/2 HGB-206 Protocol and Manufacturing of Lentiglobin for Sickle Cell Disease (SCD; bb1111) Gene Therapy (GT)

Mark C. Walters¹,

Alexis A. Thompson²,

Markus Y. Mapara³

et al.

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Polyclonality Strongly Correlates with Biologic Outcomes and Is Significantly Increased Following Improvements to the Phase 1/2 HGB-206 Protocol and Manufacturing of Lentiglobin for Sickle Cell Disease (SCD; bb1111) Gene Therapy (GT)

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