Polycations. 23. Antimicrobial Surfaces for Prevention of Pathogen Transmission

Abstract

The continued evolution of bacterial and fungal species poses a significant difficulty for the treatment of disease of microbial origin. Given this situation, the prevention of transmission of such microbial diseases becomes of increasing importance. Efforts of this laboratory have been directed toward the destruction of microbial species on environmental surfaces as a prophylaxis toward infection, and we herein report on the efficacy of a system that demonstrates activity against both Gram-positive and Gram-negative bacteria, as well as fungi. We report specifically herein on the use of fabric materials so activated for the destruction of these microbial species, useful for a variety of surfaces within hospital and related settings wherein transmission of microbial disease is a major problem, while these approaches are also applicable for a variety of other types of surfaces.

Cyclodextrin Glycosides as Materials for Removal of Pathogenic Materials from the Human Environment

“…Efforts of our laboratories at Queens College over the past several years have resulted in the development of processes that render a wide range of surfaces antibacterial and antifungal, and in certain instances, antiviral [1][2][3][4][5][6][7][8][9][10][11][12][13][14][15][16]. Specific application of these efforts to diverse surfaces can greatly alleviate health difficulties that have arisen recently, primarily owing to resistant bacteria and fungi being transmitted from person to person indirectly.…”