Polyacrylamide Hydrogel (Bulkamid) in Female Patients of 80 or More Years with Urinary Incontinence

Vecchioli-Scaldazza, Carlo; Morosetti, Carolina; Azizi, B; Giannubilo, Willy; Ferrara, Vincenzo

doi:10.1590/s1677-5538.ibju.2014.01.06

Cited by 11 publications

(32 citation statements)

References 18 publications

Supporting

Mentioning

Contrasting

Order By: Relevance

“…Even the less frequent adverse effects such as chronic urinary retention did not persist on a long-term basis (>1 year). The safety of PAHG has also been studied in women over 80 years and seems to be both effective and result in low morbidity [24]. Moreover, this study also confirmed that PAHG was effective regardless of the presence or absence of urethral hypermobility [24].…”

Section: Findings Of Our Studysupporting

confidence: 68%

“…The safety of PAHG has also been studied in women over 80 years and seems to be both effective and result in low morbidity [24]. Moreover, this study also confirmed that PAHG was effective regardless of the presence or absence of urethral hypermobility [24]. Another study showed that PAHG used for treatment of stress incontinence showed improvement in sexual function and sexual satisfaction.…”

Section: Findings Of Our Studysupporting

confidence: 56%

“…We included 8 studies with a total of 767 patients who received treatment with PAHG [16, [18][19][20][21][22][23][24]. Among these studies, six were prospective observational, one was retrospective Fig.…”

Section: Included Studiesmentioning

confidence: 99%

“…Certain studies, however, failed to support their results with objective criteria [21,22]. Two studies used urodynamic testing before and after treatment [19,24], whereas the rest used self-assessment and 24-h pad tests [16,18,20,23]. Three studies reported subjective success with improvement in the mean leakage per 24 h [16, 19,20].…”

Section: Findings Of Our Studymentioning

confidence: 99%

“…Three studies reported subjective success with improvement in the mean leakage per 24 h [16, 19,20]. All of the four studies showed a statistically significant improvement in leakage with a p value<0.001 [17,19,20,24]. A study by Lose et al showed a drop in the median leakage/ 24 h from 29 g at baseline to 4 g at 12 months (p < 0.001) [16].…”

Section: Findings Of Our Studymentioning

confidence: 99%

See 4 more Smart Citations

Polyacrylamide hydrogel (Bulkamid®) for stress urinary incontinence in women: a systematic review of the literature

et al. 2015

View full text Add to dashboard Cite

show abstract

Section: Findings Of Our Studysupporting

confidence: 68%

Section: Findings Of Our Studysupporting

confidence: 56%

Section: Included Studiesmentioning

confidence: 99%

Section: Findings Of Our Studymentioning

confidence: 99%

Section: Findings Of Our Studymentioning

confidence: 99%

See 3 more Smart Citations

Polyacrylamide hydrogel (Bulkamid®) for stress urinary incontinence in women: a systematic review of the literature

et al. 2015

View full text Add to dashboard Cite

show abstract

Factors associated with polyacrylamide hydrogel outcomes in women with stress urinary incontinence

et al. 2023

View full text Add to dashboard Cite

Knowledge of factors associated with superior outcomes in women treated with urethral bulking agents for stress urinary incontinence (SUI) remains limited. The aim of this study was to examine associations between post-treatment outcomes in women who had undergone polyacrylamide hydrogel injections for SUI, and physiological and self-reported variables captured during pre-treatment clinical evaluation. A cross-sectional study was undertaken in female patients treated for SUI with polyacrylamide hydrogel injections by a single urologist between January 2012 and December 2019. Post-treatment outcome data were gathered in July 2020 using the Patient Global Impression of Improvement (PGI-I), Urinary Distress Inventory-short form (UDI-6), Incontinence Impact Questionnaire (IIQ7), and International Consultation on Incontinence Questionnaire Short Form (ICIQ SF). All other data were gathered from women's medical records including pre-treatment patient-reported outcomes. Associations between post-treatment outcomes and pre-treatment physiological and self-reported variables were investigated using regression models. One hundred seven of the 123 eligible patients completed post-treatment patientreported outcome measures. Mean age was 63.1 years (range 25-93 years), and median time between first injection and follow-up was 51 months (inter-quartile range 23.5-70 months). Fifty-five (51%) women had a successful outcome based on PGI-I scores. Women with type 3 urethral hypermobility pre-treatment were more likely to report treatment success (PGI-I). Poor bladder compliance pre-treatment was associated with greater urinary distress, frequency and severity (UDI-6 and ICIQ) post-treatment. Older age was associated with worse urinary frequency and severity (ICIQ) post-treatment. Associations between patient-reported outcomes and time between first injection and follow-up were trivial and not statistically significant.Severity of pre-treatment incontinence impact (IIQ-7) was associated with worse incontinence impact post-treatment. Type 3 urethral hypermobility was associated with a successful outcome, whereas pre-treatment incontinence impact, poor bladder compliance and older age were associated with poorer self-reported outcomes.Long-term efficacy appears to hold in those who responded to initial treatment.

show abstract

A comprehensive review on hydrogel materials in urology: Problems, methods, and new opportunities

et al. 2022

View full text Add to dashboard Cite

Hydrogel materials provide an extremely promising group of materials that can find an increasingly wide range of use in treating urinary system conditions due to their unique properties. The present review describes achievements to date in terms of the use and development prospects of hydrogel materials applications in the treatment and reconstruction of the urinary system organs, which among others include: hydrogel systems of intravesical drug delivery, ureteral stents design, treatment of vesicoureteral reflux, urinary bladder and urethral defects reconstruction, design of modern urinary catheters and also solutions applied in urinary incontinence therapy (Figure 4). In addition, hydrogel materials find increasingly growing applications in the construction of educational simulation models of organs and specific conditions of the urinary system, which enable the education of medical personnel. Numerous research efforts are underway to expand the existing treatment methods and reconstruction of the urinary system based on hydrogel materials. After conducting the further necessary research, many of the innovative solutions developed to date have high application potential.

show abstract

Polyacrylamide Hydrogel (Bulkamid) in Female Patients of 80 or More Years with Urinary Incontinence

Abstract: Polyacrylamide hydrogel (Bulkamid®) is an effective treatment with low morbility in patients of 80 or more years.

Cited by 11 publications

References 18 publications

Polyacrylamide hydrogel (Bulkamid®) for stress urinary incontinence in women: a systematic review of the literature

Polyacrylamide hydrogel (Bulkamid®) for stress urinary incontinence in women: a systematic review of the literature

Factors associated with polyacrylamide hydrogel outcomes in women with stress urinary incontinence

A comprehensive review on hydrogel materials in urology: Problems, methods, and new opportunities

Contact Info

Product

Resources

About